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Annals of Surgical Oncology

, Volume 25, Supplement 3, pp 697–698 | Cite as

ASO Author Reflections: Eighty is the New Sixty—Breast Cancer Treatment Strategies in the Octogenarian Patient Population

  • Ranjna SharmaEmail author
ASO Author Reflections

Past

As the population ages and life expectancy increases, many women are living longer, healthier lives.1 Breast cancer diagnoses are also on the rise in older populations given this longevity.2 It has been estimated that 12% of the population will develop breast cancer over the course of their lifetimes, with women aged 65 years and over at greatest risk as increasing age is a known risk factor for the development of breast cancer. Historically, octogenarians have not been included in research studies examining oncologic therapy efficacy in robust numbers. Thus, it is challenging to know what therapies may be effective and necessary to treat breast cancer in this patient population.2,3

Present

Our group studied this patient population and their treatment patterns at our institution over a 10-year period in a retrospective fashion.4,5Our study cohort included 187 octogenarian patients compared with a younger cohort of 169 patients, examining clinicopathologic tumor characteristics...

Notes

Disclosure

Ranjna Sharma has no conflicts of interest to disclose.

References

  1. 1.
    Barginear MF, Muss H, Kimmick G, et al. Breast cancer and aging: results of the U13 conference breasts cancer panel. Breast Cancer Res Treat. 2014;146(1):1–6.CrossRefGoogle Scholar
  2. 2.
    Schonberg MA, Silliman, RA, McCarthy EP, Marcantonio ER. Factors noted to affect women aged 80 and older’s breast cancer treatment decisions. Breast Cancer Res Treat. 2014;145(1):211–23.CrossRefGoogle Scholar
  3. 3.
    Cortadellas T, Gascon A, Cordoba O, et al. Surgery improves breast cancer-specific survival in octogenarians with early-stage breast cancer. Int J Surg. 2013;11(7): 554–7.CrossRefGoogle Scholar
  4. 4.
    Mamtani A, Gonzalez JJ, Neo DT, et al. Treatment strategies in octogenarians with early-stage, high-risk breast cancer. Ann Surg Oncol. 2018;25:1495–501.CrossRefGoogle Scholar
  5. 5.
    Mamtani A, Gonzalez JJ, Neo D, et al. Early-stage breast cancer in the octogenarian: tumor characteristics, treatment choices, and clinical outcomes. Ann Sur Oncol. 2016;23(10):3371–8.CrossRefGoogle Scholar
  6. 6.
    Wickberg A, Liljegren G, Killander F, et al. Omitting radiotherapy in women > 65 years with low-risk early breast cancer after breast-conserving surgery and adjuvant endocrine therapy is safe. Eur J Surg Oncol. 2018;44(7):951–6.CrossRefGoogle Scholar
  7. 7.
    Coates AS, Winer EP, Goldhirsch A, et al. Tailoring therapies—improving the management of early breast cancer: St Gallen International Expert Consensus on the primary therapy of early breast cancer 2015. Ann Oncol. 2015;26(8):1533–46.CrossRefGoogle Scholar

Copyright information

© Society of Surgical Oncology 2018

Authors and Affiliations

  1. 1.Department of Surgery, Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonUSA

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