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Table IV 3(3-1) Fractional Factorial Experimental Design Scheme Applied in the Investigation of the Influence of Main Compression Force, Tableting Speed, and Amount of Punches on Tablet CQAs

From: Implementing the Design of Experiments (DoE) Concept into the Development Phase of Orodispersible Minitablets (ODMTs) Containing Melatonin

Run number Independent variable
Main compression force (kN) Table speed (rpm) Amount of punches (pcs)
1 −1 −1 −1
2 −1 0 1
3 −1 1 0
4 0 −1 1
5 0 0 0
6 0 1 −1
7 1 −1 0
8 1 0 −1
9 1 1 1
10C 0 0 0
11C 0 0 0
12C 0 0 0