Table 2 Changes in primary and secondary outcomes in 26 patients completing the intervention

From: Brief psychotherapy administered by non-specialised health workers to address risky substance use in patients with multidrug-resistant tuberculosis: a feasibility and acceptability study

Questionnaire Baseline
Med (IQR)
Follow-up
Med (IQR)
ASSISTb (alcohol and substance use)
 Highest scorea 17.5 (15–24) 6 (6–8)
 Alcohol 17.5 (15–23) 6 (6–8)
 Cannabis 0 (0–6) 0 (0–6)
 Amphetamines 0 (0–0) 0 (0–0)
CES-D (depression) 23.5 (18–34) 17 (13–22)
FTNDc (nicotine dependence) 2 (2–4) 1 (1–2)
EQ-5D 3L (health status
 Descriptive elements 5.5 (5–7) 5 (5–5)
 Visual analogue scale 70 (57–80) 90 (80–100)
SHS (disability)
 Work/school 0 (0–3) 0 (0–0)
 Social life 2.5 (0–5) 0 (0–3)
 Family life/home responsibilities 4 (0–7) 0 (0–3)
SRQ-20 (psychological distress) 8 (4–10) 3 (1–4)
SOCRATES (readiness for change)
 Recognition 20 (19–22) 15 (15–19)
 Ambivalence 13 (11–15) 8 (4–10)
 Taking steps 35 (32–39) 40 (38–40)
MDSPSS (social support)
 Significant other 8 (4–10) 3 (1–4)
 Family 7 (6–7) 7 (6–7)
 Friends 6 (4–6) 5 (4–6)
 Total 6 (5–6) 6 (6–7)
  1. Abbreviations: ASSIST Alcohol, Smoking and Substance Involvement Screening Test, a measure of problematic alcohol and drug use [23], CESD-D Centre for Epidemiological Studies Depression Scale, a measure of the most common symptoms of depression [27], FTND Fagerström Test for Nicotine Dependence, a measure of the intensity of physical addition to nicotine [28], EQ-5D 3L, a standardised instrument combining both descriptive (lower score indicates better health) and visual components as a measure of health outcome [29], SDS Sheehan Disability Scale, a measure of functional impairment in three inter-related domains: work, social and family life [30], SRQ-20 Self-Reporting Questionnaire 20 (SRQ20), a World Health Organisation screening test for anxiety and depression disorders [31], SOCRATES Stages of Change Readiness and Treatment Eagerness Scale, an experimental instrument designed to assess readiness for change [32], and MSPSS Multidimensional Scale of Perceived Social Support, a brief self-report questionnaire with 12 items that subjectively measure perceived social support using three subscales, namely, family, friends and significant others (MSPSS) [33]
  2. aFour (15%) patient regularly used more than one substance before the intervention; the substance with the highest ASSIST score was used
  3. bNo patient reported sedative, hallucinogen, opiate or methaqualone use
  4. cOf the 11 smoking patients who scored > 1 on the Fagerström test at baseline