Table 2 Relatedness of different types of pairwise relationship. “Kinship” was produced with PLINK, and Kinship-homog was calculated with “homog” mode of KING. “mrs” was defined as the number of identical genotypes of shared loci divided by the total number of common non-reference loci between a pair of samples. “Type” is defined as “MZD,” replicated of the same biological sample; “1st” and “NR” indicate a similar biological relationship between first-degree relationship as a sibling or no genetic relationship. The suffix of “major” and “minor” indicate the components of plasma sample after deconvolution
From: cfDNA deconvolution via NIPT of a pregnant woman after bone marrow transplant and donor egg IVF
Lib-Pair | mrs | Kinship | Kinship-homog | Type |
---|---|---|---|---|
W0120237005-W0120237004major | 0.951219512 | 0 | −0.3474 | MZD |
W0120237006-W0120237007 | 0.907407407 | 0 | −0.271 | MZD |
W0120237003-W0120237005 | 0.902439024 | 0 | −0.0113 | MZD/1st |
W0120237007-W0120237004minor | 0.777777778 | 0 | −0.9107 | 1st |
W0120237003-W0120237004major | 0.755102041 | 0 | −0.4752 | 1st |
W0120237005-W0120237004minor | 0.707317073 | 0 | −0.719 | NR |
W0120237004major-W0120237004minor | 0.693877551 | 0 | −0.3071 | NR |
W0120237006-W0120237008 | 0.690909091 | 0 | −0.0746 | 1st |
W0120237007-W0120237008 | 0.685185185 | 0 | −0.6575 | 1st |
W0120237007-W0120237004major | 0.666666667 | 0 | −1.1214 | NR |
W0120237005-W0120237008 | 0.585365854 | 0 | −0.4468 | NR |
W0120237006-W0120237004major | 0.571428571 | 0 | −0.6758 | NR |
W0120237008-W0120237004minor | 0.563106796 | 0 | −0.6385 | MZD/NR |
W0120237006-W0120237004minor | 0.563106796 | 0 | −0.5314 | 1st/NR |
W0120237005-W0120237006 | 0.56097561 | 0 | −0.2095 | NR |
W0120237008-W0120237004major | 0.540816327 | 0 | −0.8303 | NR |
W0120237003-W0120237007 | 0.518518519 | 0 | −0.8658 | NR |
W0120237005-W0120237007 | 0.512195122 | 0 | −0.7805 | NR |
W0120237003-W0120237006 | 0.509090909 | 0 | −0.2 | NR |
W0120237003-W0120237008 | 0.473333333 | 0 | −0.3805 | NR |
W0120237003-W0120237004minor | 0.436893204 | 0 | −0.8847 | 1st/NR |