Fig. 8 | Diabetology & Metabolic Syndrome

Fig. 8

From: Experimental dopaminergic neuron lesion at the area of the biological clock pacemaker, suprachiasmatic nuclei (SCN) induces metabolic syndrome in rats

Fig. 8

Peri-SCN area dopaminergic lesion induced increases in blood pressure and heart rate. Animals received an infusion of 6-OHDA (2–4 μg/side) at the peri-SCN area bilaterally. The systolic and diastolic blood pressures (a), and heart rate (b) were measured in rats at 16 weeks after 6-OHDA lesion (n = 14) or sham lesion (n = 8) to the peri-SCN area. Data are represented as the mean ± SEM. *Significant difference between treatment groups (P < 0.05, unpaired Student’s t-test)

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