Fig. 6 | Diabetology & Metabolic Syndrome

Fig. 6

From: Experimental dopaminergic neuron lesion at the area of the biological clock pacemaker, suprachiasmatic nuclei (SCN) induces metabolic syndrome in rats

Fig. 6

Peri-SCN area dopaminergic lesion increased body weight gain and abdominal body fat. Animals received an infusion of 6-OHDA (2–4 μg/side) at the peri-SCN area bilaterally. Body weight over 17 weeks after 6-OHDA lesion (n = 14) or vehicle sham lesion (n = 8) to SCN area (a). Parametrial fat pad weight (b) and retroperitoneal fat pad weight (c) at the end of experiment (week 17). Data are represented as the mean ± SEM. * P < 0.05 or ** P  < 0.01 significant difference between treatment groups (unpaired Student’s t-test)

Back to article page