Table 3 Antimicrobial screening results of the synthesized 1,2,4-triazole derivatives (T1T20)

From: Synthesis and biological evaluation of heterocyclic 1,2,4-triazole scaffolds as promising pharmacological agents

Compound Minimum inhibitory concentration (µM)
Bacterial strain Fungal strain
Gram +ve Gram −ve
B. substilis P. aeruginosa E. coli C. albican A. niger
T1 120.5 241.1 241.1 241.1 120.5
T2 56.4 56.4 112.9 225.9 225.9
T3 58.3 58.3 116.6 233.2 116.6
T4 52.6 52.6 105.3 52.6 105.3
T5 24.7 12.3 24.7 12.3 99.0
T6 108.5 54.2 54.2 108.5 217.0
T7 116.1 29.0 116.1 232.2 232.2
T8 116.1 58.0 58.0 116.1 232.2
T9 54.6 27.3 54.6 109.2 218.4
T10 55.6 55.6 111.3 222.6 55.6
T11 55.6 111.3 111.3 27.8 111.3
T12 103.4 51.7 103.4 206.8 103.4
T13 101.3 202.6 202.6 101.3 202.6
T14 50.6 101.3 101.3 202.6 101.3
T15 54.3 108.7 217.5 217.5 54.3
T16 108.7 108.7 217.5 217.5 217.5
T17 54.3 217.5 217.5 108.7 27.1
T18 104.0 52.0 104.0 208.0 104.0
T19 113.4 226.9 56.7 113.4 113.4
T20 61.7 123.5 61.7 247.1 247.1
Fluconazole 40.8 20.4
Ciprofloxacin 18.0 18.0 37.7
Amoxicillin 17.1 17.1 17.1
  1. Italics signifies the most active compound in comparison to the standard compound