Skip to main content

Table 1 Studies on HPV16 variants in head and neck cancers

From: Human papillomavirus genome variants and head and neck cancers: a perspective

Study Country N HPV16 + samples Seq. Variant lineage (n) Non lineage specific variants (n)
Gillison 2000 [67] USA 52 HNC E6 39 Eur; 9 Asian; 2 NA; 1 Afr-1 20 T350G 6 A131G
Hoffmann 2004 [70] DE 21 HNC (5 OPC) E6/E7   8 T350G (2 in OPC) 7 A131G (1 in OPC)
Badaracco 2007 [62] IT 13 HNC (5 TC) L1 9 Eur 2 Af-2; 1 AA  
Agrawal 2008 [61] USA 14 HNC E6 13 Eur 1 As 3 T350G
Boscolo Rizzo 2009 [68] IT 8 HNC (4 OPC) E6   5 T350G
Blakaj 2012 [65] USA 43 HNC (28 OPC) E6 31 Eur 7 AA; 3 Af  
Du 2012 [66] SW 108 TC E6 51(/55) EUR 43 T350G 21 A131G
Barbieri 2014 [63] IT 51 OPC L1 41 Eur 10 Af  
Hassani 2015 [69] JP 10 TC E6   8 T350G (1/3 T350G in tonsillitis)
Betiol 2016 [64] BR 21 HNC (3 OPC) E6 12 Eur 9 AA or NA1  
  1. Abbreviations: HNC Head and neck cancer, OPC Oropharyngeal cancer
  2. Countries: BRBrazil, DE Germany, IT Italia, JP, Japan, SW Sweden
  3. HPV variant lineages: EUR European, A Asian, AA Asian American, NA North American, Af African