Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Protein signature of human skin fibroblasts allows the study of the molecular etiology of rare neurological diseases

Fig. 1

Overview of subcellular compartments (a, b) and NMDs (c) covered by the created fibroblast library: a, b Presentation of the different subcellular fibroblast compartments including the corresponding number of proteins identified to be localized to these respective compartments. While some proteins are exclusively present in one compartment, a considerable number of such localized to different/multiple compartments is covered in the library. Proteins listed for the subcellular compartments illustrated in b might be also covered in a as being resident to membranes or the cytosol. c Illustrates the distribution of proteins identified for certain NMDs along the neuromuscular axis including motoneuron and peripheral nervous system diseases, defects in neuromuscular transmission and muscular disorders

Back to article page