Table 2 Summary of dosimetric results for OARs analyzed from dose-volume histogram

From: Feasibility of a mini-pig model of radiation-induced brain injury to one cerebral hemisphere

  P1 P2 P3 P4
Summary of dosimetric results for OARs analyzed from dose-volume histogram
Brainstem (Vmean = 3.9 cm3)
D2% (Gy) 22.4 17.7 10.1 10.4
Dmean (Gy) 11.3 9.6 3.6 3.0
V10/12 (%) 53/34 37/20  < 3.4  < 3.3
Cerebellum (Vmean = 4.3 cm3)
D2% (Gy)    11.1 10.5
Dmean (Gy)    3.4 3.4
V10/12 (%)    4.6 4.1
Optic chiasm (Vmean = 0.1 cm3)
D2% (Gy) 24.7 23.7 11.0 9.3
Dmean (Gy) 22.9 22.0 10.0 6.7
V6/8/10 (%) 1.0 1.0  ≤ 1.0  < 0.5
Left optic nerve (Vmean = 0.1 cm3)
D2% (Gy) 22.1 23.2 10.4 7.4
Dmean (Gy) 17.9 17.4 9.2 6.0
V6/8/10 (%) 1.0 1.0  ≤ 1.0  ≤ 0.5
Right optic nerve (Vmean = 0.1 cm3)
D2% (Gy) 20.2 19.1 9.0 4.5
Dmean (Gy) 16.9 14.2 8.3 3.8
V6/8/10 (%) 0.1 0.1 0.1 0.1
Spinal cord (Vmean = 3.7 cm3)
D2% (Gy) 5.5 3.3  < 1  < 1
Dmean (Gy) 1.0 0.6 0.2 0.2
V8/10/12 (%)  < 0.3 0 0 0
Left lens (Vmean = 0.2 cm3)
Dmax (Gy) 3.4 1.4  < 0.1  < 0.1
Right lens (Vmean = 0.2 cm3)
Dmax (Gy) 5.6 2.7 1.7 1.5
Brain – PTV (P1&P2) (Vmean = 30 cm3)
D2% (Gy) 22.5 18   
Dmean (Gy) 11 7.7   
V10/12 (%) 49/35 52/32   
Brain – PTV (P3&P4) (Vmean = 36.6 cm3)
D2% (Gy)    10.7 11.4
Dmean (Gy)    5.3 5.3
V10/12 (%)     ≤ 4  ≤ 8
  1. Dx% = dose received by the x% of the volume; Dmean = mean dose received by the volume; Vx (VATD) = volume receiving at least x Gy; Vmean = mean structure volume of the four pigs; Dmax = maximum point dose