Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Changes of blood-brain-barrier function and transfer of amyloid beta in rats with collagen-induced arthritis

Fig. 2

Changes in the integrity and permeability of brain microvessels of CIA rats. a Representative images of ZO-1 immunostaining in the cortex and the hippocampus of CIA rats and controls. The quantitative results of ZO-1 immunostaining are shown on the right-hand side of the images. b and c Immunoblotting and the quantitative densitometric analyses of ZO-1 (b) and occludin (c) in the lysate of the isolated brain microvessels. d BBB permeability measured by the extraction ratio of sodium fluorescein. The data are given as the mean ± SEM of 3-4 experiments. *P < 0.05 compared with controls

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