Table 3 Risk of myocardial infarction, ischemic stroke, and all-cause death in patients with diabetes and their matched general population comparison cohort

From: Ten-year cardiovascular risk in diabetes patients without obstructive coronary artery disease: a retrospective Western Denmark cohort study

  Patients Events 10-year cumulative incidencea (95% CI) Risk differencea
(95% CI)
Unadjusted HR (95% CI) Adjusted HRb (95% CI) Adjusted HRc (95% CI)
Myocardial infarction
 General population 28,670 595 2.9% (2.7–3.1) Reference Reference Reference Reference
 Diabetes patients 5734 134 3.2% (2.7–3.8) 0.3% (-0.3–0.9) 1.26 (1.04–1.52) 1.07 (0.84–1.36) 0.93 (0.72–1.20)
Ischemic stroke
 General population 28,670 456 2.2% (2.0–2.4) Reference Reference Reference Reference
 Diabetes patients 5734 230 5.2% (4.5–5.9) 3.0% (2.3–3.7) 2.96 (2.51–3.50) 2.04 (1.65–2.52) 1.87 (1.47–2.38)
Death
 General population 28,670 3659 17.8% (17.2–18.3) Reference Reference Reference Reference
 Diabetes patients 5734 1228 29.6% (28.1–31.1) 11.8% (10.2–13.4) 1.88 (1.76–2.01) 1.58 (1.45–1.72) 1.24 (1.13–1.36)
  1. CAG coronary angiography, CI confidence interval, CIP cumulative incidence proportion, HR hazard ratio
  2. aLimited to the 75th percentile of follow-up (10 years). In myocardial infarction and ischemic stroke, accounting for the competing risk of death
  3. bAdjusted for myocardial infarction within 30 days of angiography, statin treatment, oral anticoagulant treatment, and antiplatelet treatment
  4. cAdjusted for peripheral artery disease, hypertension, chronic obstructive pulmonary disease, myocardial infarction within 30 days of angiography, statin treatment, oral anticoagulant treatment, and antiplatelet treatment. In case of ischemic stroke and death, additionally adjusted for congestive heart failure, previous ischemic stroke/TIA, and atrial fibrillation