Table 4 The result of the evaluation of candidate case definitions for type 1 diabetes

From: Performance evaluation of case definitions of type 1 diabetes for health insurance claims data in Japan

Case definition N (%)e Performance values (95% CI)
Sensitivity PPV F-score
1. ① ICD10 code of E10a 305 (0.268) 32.9 (28.4, 37.2) 33.3 (28.0, 38.4) 0.331 (0.285, 0.373)
2. ② Claims code of injector needlesb 154 (0.135) 32.3 (27.9, 36.6) 64.8 (58.9, 70.6) 0.431 (0.382, 0.475)
3. ③ Claims codes of basal insulinc 1392 (1.224) 40.2 (36.1, 44.5) 8.9 (7.6, 10.3) 0.146 (0.126, 0.166)
4. ④ Claims codes of syringe pumpd 14 (0.012) 3.9 (1.9, 6.0) 86.2 (68.0, 99.0) 0.075 (0.037, 0.112)
5. ① as well as ② 73 (0.064) 21.4 (17.0, 25.4) 90.4 (85.0, 94.8) 0.346 (0.286, 0.399)
6. ① as well as ③ 136 (0.120) 25.9 (21.7, 30.1) 58.8 (51.0, 66.2) 0.360 (0.307, 0.411)
7. ① as well as ④ 12 (0.011) 3.6 (1.7, 5.5) 92.2 (79.0, 99.4) 0.069 (0.034, 0.103)
8. ① as well as (③ or ④) 138 (0.121) 26.4 (22.0, 30.5) 58.9 (51.0, 66.2) 0.364 (0.310, 0.414)
9. ① as well as (② or ④) 81 (0.071) 23.7 (19.5, 27.9) 90.2 (85.2, 94.4) 0.375 (0.319, 0.427)
10. ① as well as (② or ③) 136 (0.120) 25.9 (21.7, 30.1) 58.8 (51.0, 66.2) 0.360 (0.307, 0.411)
11. ① as well as (② or ③ or ④) 136 (0.120) 26.4 (22.0, 30.5) 58.9 (51.0, 66.2) 0.364 (0.310, 0.414)
  1. CI confidence interval, NPV negative predictive value, PPV positive predictive value
  2. aConfirmed disease name of type 1 diabetes based on ICD10 code
  3. bThe claims code of injector needles for type 1diabetes
  4. cThe claims codes of basal insulin
  5. dThe claims codes of syringe pump for continuous subcutaneous insulin infusion
  6. eNumber of cases who fell within the case definitions in the test data (prevalence within the test data)