Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Baicalein inhibits inflammatory response and promotes osteogenic activity in periodontal ligament cells challenged with lipopolysaccharides

Fig. 5

Baicalein restores the osteogenesis of PDLCs challenged with LPS. Cells were pre-treated with baicalein (20, 40, or 80 μM) for 2 h prior to incubation with or without LPS for 24 h. Baicalein effectively increased the ALP (a) and ARS (b) staining of LPS-treated PDLCs. The mRNA (c) and protein (d) expressions of COL-1, RUNX2 and OSX were dose-dependently up-regulated by baicalein. *p < 0.05, **p < 0.01, statistical significant difference in comparison to cells treated with LPS alone.

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