Table 1 Baseline characteristics of study participants

From: The comparison effects of intra-articular injection of Platelet Rich Plasma (PRP), Plasma Rich in Growth Factor (PRGF), Hyaluronic Acid (HA), and ozone in knee osteoarthritis; a one year randomized clinical trial

  Total
(n = 200)
PRP
(n = 52)
PRGF
(n = 51)
HA
(n = 49)
Ozone
(n = 48)
Baseline characteristics
 Age (yr),Mean ± SD 56.9 ± 6.3 56.09 ± 6.0 56.07 ± 6.3 57.91 ± 6.7 57.60 ± 6.1
 Sex (Male/Female) 61/139 13/39 14/37 12/37 12/36
 BMI (kg/m2), Mean ± SD 28.24 ± 2.8 27.41 ± 2.6 27.50 ± 2.1 27.46 ± 2.2 27.01 ± 1.9
 Duration of pain (yr), Mean ± SD 4.41 ± 2.2 4.44 ± 2.3 4.9 ± 2.7 3.86 ± 1.6 4.42 ± 2.1
 Side of injection (left/right) 93/107 22/30 18/33 28/21 25/23
 Degree of osteoarthritis (2/3) 108/92 26/26 28/23 27/22 27/21
 History physiotherapy, n(%) 119 (59.5) 29 (55.8) 36 (70.6) 26 (53.1) 28 (42.3)
 History injection, n(%) 92 (46.0) 22 (44.3) 25 (49.0) 24 (49.0) 21 (58.3)
 Pain during injection, Mean ± SD 2.43 ± 2.0 2.80 ± 2.2 3.07 ± 2.6 1.81 ± 1.3 1.95 ± 1.18
Outcome measures
 VAS, Mean ± SD 8.03 ± 1.2 7.92 ± 1.0 7.90 ± 1.3 8.22 ± 1.1 8.10 ± 1.0
WOMAC, Mean ± SD
 Pain 9.54 ± 1.6 9.69 ± 1.3 9.72 ± 1.7 9.44 ± 1.6 9.29 ± 1.8
 Function 30.68 ± 7.3 30.19 ± 6.4 30.54 ± 7.6 31.02 ± 8.8 31.00 ± 6.1
 Stiffness 2.73 ± 1.3 2.84 ± 1.1 2.84 ± 1.6 2.71 ± 1.1 2.50 ± 1.1
 Total 42.85 ± 9.2 42.73 ± 7.7 43.11 ± 9.6 42.75 ± 11.1 42.79 ± 8.2
LEQ, Mean ± SD
 Pain 5.31 ± 1.0 5.17 ± 1.0 5.13 ± 1.1 5.55 ± 0.9 5.41 ± 1.0
 Walk 1.65 ± 0.8 1.65 ± 0.6 1.66 ± 0.8 1.71 ± 0.9 1.56 ± 0.7
 ADL 5.71 ± 0.7 5.75 ± 0.6 5.71 ± 0.7 5.70 ± 0.8 5.67 ± 0.7
 Total 12.65 ± 2.0 12.58 ± 1.6 12.62 ± 2.1 12.76 ± 2.2 12.65 ± 2.0
  1. Abbreviations: SD standard deviation; PRGF plasma rich in growth factor; PRP platelet-rich plasma; HA hyaluronic acid; VAS visual analog scale; WOMAC Western Ontario and McMaster Universities Osteoarthritis Index; LEQ Lequesne Index