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BMC Cancer

, 18:437 | Cite as

Correction to: Sepsis increases perioperative metastases in a murine model

  • Lee-Hwa Tai
  • Abhirami A. Ananth
  • Rashmi Seth
  • Almohanad Alkayyal
  • Jiqing Zhang
  • Christiano Tanese de Souza
  • Phillip Staibano
  • Michael A. Kennedy
  • Rebecca C. Auer
Open Access
Correction

Correction

It has been highlighted that the original manuscript [1] contains a typesetting error in Fig. 1 and the Fig. 1c panel has been inadvertently duplicated in panel Fig. 1d. This does not affect the results and conclusions of the article. The correct version of Fig. 1 is included with this Correction. The original article has been updated.
Fig. 1

Hemorrhagic shock does not increase metastatic disease. a Experimental overview. BALB/c mice were bled through the saphenous vein (indicated by the white arrow) and subsequently injected intravenously (IV) through the tail vein with 3 × 105 CT26LacZ cells. Approximately 1 h later, surgical stress (sx) was generated by laparotomy (Lap) (5 cm incision). Mice were sacrificed at 72 h to quantify lung metastases. b Blood pressure is reduced following surgical stress and blood loss. Blood pressure (mmHg) was measured following a 5-day training period (Day 1–5), prior to bleeding (Pre), immediately following bleeding (Post-BL), and immediately following surgical stress (Post-Sx and BL, n = 3). c Blood loss increases metastatic burden. Lung metastases were measured on Day 3 following no blood loss (no BL, n = 3) or 20% (20% BL, n = 3) or 30% blood loss (30% BL, n = 4). d Blood loss does not increase metastatic disease in conjunction with surgical stress. Lung metastases were measure on Day 3 in mice that did not undergo surgical stress (No Sx, n = 5) and animals undergoing a laparotomy (Lap, n = 4) alone or in combination with 30% blood loss (Lap + 30% BL, n = 5). Error bars represent ± SEM

Reference

  1. 1.
    Tai LH, et al. Sepsis increases perioperative metastases in a murine model. BMC Cancer. 2018;18:277.  https://doi.org/10.1186/s12885-018-4173-4.CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors and Affiliations

  • Lee-Hwa Tai
    • 1
  • Abhirami A. Ananth
    • 1
    • 2
  • Rashmi Seth
    • 3
  • Almohanad Alkayyal
    • 1
    • 2
    • 4
  • Jiqing Zhang
    • 2
    • 5
    • 6
  • Christiano Tanese de Souza
    • 2
  • Phillip Staibano
    • 2
  • Michael A. Kennedy
    • 2
  • Rebecca C. Auer
    • 1
    • 2
    • 3
    • 7
  1. 1.Deparment of Biochemistry, Microbiology, and Immunology, Faculty of MedicineUniversity of OttawaOttawaCanada
  2. 2.Center for Innovative Cancer Research, Ottawa Hospital Research InstituteOttawaCanada
  3. 3.Department of Surgery, Division of General SurgeryUniversity of OttawaOttawaCanada
  4. 4.Department of Medical Laboratory TechnologyUniversity of TabukTabukSaudi Arabia
  5. 5.Department of NeurosurgeryThe Second Hospital of Shandong UniversityShandongChina
  6. 6.Department of Cellular and Molecular Medicine, Faculty of MedicineUniversity of OttawaOttawaCanada
  7. 7.Ottawa General HospitalOttawaCanada

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