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Table 1  A comparison of the characteristics between children with a positive for MP-specific IgM titer at the time of admission and those with a negative MP-specific IgM titer at the time of admission due to MP pneumonia

From: Clinical significance of Mycoplasma pneumoniae specific IgM titer in children hospitalized with Mycoplasma pneumoniae pneumonia

Variables, mean ± SD or n (%) Children positive for MP-specific IgM Children negative for MP-specific IgM Total P value
n 118 37 155 NA
Male, n (%) 55/118 (46.6) 21/37 (56.8) 76/155 (49.0) 0.281
Age at diagnosis of MP pneumonia, years 5.8 ± 3.5 6.9 ± 4.8 6.0 ± 3.8 0.176
Duration between symptom onset and admission, days 7.4 ± 3.6 4.0 ± 3.4 6.6 ± 3.8 < 0.001
Total duration of fever during the illness, days 7.6 ± 7.1 5.0 ± 4.1 7.0 ± 6.6 0.021
Total hospitalization duration, days 9.9 ± 5.5 7.9 ± 4.6 9.5 ± 5.4 0.047
Development of any extra-pulmonary symptoms, n (%) 34/118 (28.8) 2/37 (5.4) 36/155 (23.2) 0.003
Pleural effusion, yes, n (%) 21/118 (17.8) 4/37 (10.8) 25/155 (16.1) 0.313
Hemoptysis, yes, n (%) 1/118 (0.8) 3/37 (8.1)   0.015
Oxygen need, yes, n (%) 10/118 (8.5) 0/37 (0.0) 10/155 (6.5) 0.067
Respiratory virus co-infection, yes, n (%) 53/118 (44.9) 12/37 (32.4) 65/155 (41.9) 0.179
Positive results on pneumobacter PCR, n (%) 21/61 (34.4) 6/12 (50.0) 27/73 (337.0) 0.307
Respiratory virus co-infection or positive results on pneumobacter PCR, n (%) 63/118 (53.4) 15/37 (40.5) 77/155 (49.7) 0.173
Macrolide-resistant MP 92/110 (83.6) 25/36 (69.4) 117/146 (80.1) 0.403
Response to stepwise treatment for MP pneumonia, n (%) 0.042
 Good response 40/118 (33.9) 19/37 (51.4) 59/155 (38.1)  
 Slow response 59/118 (50.0) 18/37 (48.6) 77/155 (49.7)  
 No response 14/118 (11.9) 0/37 (0.0) 14/155 (9.0)  
 Progression 5/118 (4.2) 0/37 (0.0) 5/155 (3.2)  
Trend P     0.007
Severity of pneumonia based on chest radiography 0.149
 Mild 12/118 (10.2) 7/37 (18.9) 19/155 (12.3)  
 Moderate 75/118 (63.6) 25/37 (67.6) 100/155 (64.5)  
 Severe 31/118 (26.3%) 5/37 (13.5%) 36/155 (23.2)  
  1. IgM: immunoglobulin M; MP: Mycoplasma pneumoniae; n: number; NA: not applicable; PCR: polymerase chain reaction; SD: standard deviation