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Table 1 Patient characteristics

From: Validating a clinical prediction score for Legionella-related community acquired pneumonia

  Legionella CAP
n = 131
Non-Legionella CAP
n = 160
p
Male, n (%) 88 (67.2) 89 (55.6) 0.037
Age [years], median (IQR) 63.4 (56.2–70.3) 72.2 (64.7–81.4) < 0.001
Current smoker, n (%) 43 (53.8) 29 (20.1) < 0.001
Comorbidities, n (%)
 COPD 11 (8.4) 47 (29.4) < 0.001
 Congestive heart failure 11 (8.4) 21 (13.1) 0.22
 Neurologic disease 15 (11.5) 37 (23.1) 0.012
 Cancer 8 (6.1) 33 (20.6) < 0.001
 Renal disease 4 (3.1) 15 (9.4) 0.033
 Liver disease 4 (3.1) 2 (1.3) 0.271
Symptoms, n (%)
 Dyspnea 79 (68.7) 124 (83.8) 0.005
 Dry cough 77 (58.8) 50 (31.3) < 0.001
 Headache 31 (66.0) 14 (32.6) < 0.001
 Muscle or joint pain 37 (64.9) 25 (51.0) 0.143
 Nausea 36 (52.9) 28 (48.3) 0.538
 Vomiting 28 (41.8) 20 (37.0) 0.686
 Diarrhea 42 (53.2) 13 (15.5) < 0.001
 Confusion 24 (18.3) 32 (20.0) 0.718
Physical findings, median (IQR)
 Heart frequency [BPM] 100 (82–112) 96 (83–111) 0.635
 Systolic blood pressure (mmHg) 130 (118–145) 135.5 (119–151) 0.139
 Diastolic blood pressure (mmHg) 73 (65–81) 75.5 (67–83) 0.111
 Body temperature (°C) 39 (37.8–39.7) 38.4 (37.5–39.1) 0.002
CURB-65 [score 0–5], median (IQR) 1 (0–2) 2 (1–2) 0.016
Previous antibiotic treatment, n (%) 39 (33.6) 42 (26.8) 0.226
Laboratory findings, median (IQR)
 Urea (mmol/L) 7.1 (5.5–11.4) 7.2 (5.0–9.1) 0.333
 Creatinine (mc mol/L) 101 (80–131) 88 (66–108) < 0.001
 Sodium (mmol/L) 132 (129–135) 136 (133–138) < 0.001
 Potassium (mmol/L) 3.9 (3.5–4.2) 3.9 (3.6–4.3) 0.186
 Bilirubin (µmol/L) 12 (8–19) 13 (8–16) 0.628
 ASAT (IU/L) 49 (33–103) 26 (19–35) < 0.001
 ALAT (IU/L) 36 (24–67) 19 (13–29) < 0.001
 LDH (IU/L) 465 (324–609) 198 (168–238) < 0.001
 AP (IU/L) 79 (69–115) 82 (67–113) 0.242
 GGT (IU/L) 47 (30–79) 37 (24–67) 0.034
 C-reactive protein (mg/L) 317 (244–390) 162 (77–260) < 0.001
 Hemoglobin (mmol/L) 8.3 (7.8–9.1) 8.1 (7.3–8.9) 0.067
 Platelets (× 109/L) 204 (156–249) 221 (179–293) 0.002
 White blood cell count (× 109/L) 13 (10–17) 13 (10–18) 0.377
  1. CAP community acquired pneumonia, IQR interquartile range, BPM beats per minute, ASAT aspartate transaminase, ALAT alanine transaminase, LDH lactate dehydrogenase, AP alkaline phosphatase, GGT gamma-glutamyltransferase