|
Male, n (%)
|
88 (67.2)
|
89 (55.6)
|
0.037
|
|
Age [years], median (IQR)
|
63.4 (56.2–70.3)
|
72.2 (64.7–81.4)
|
< 0.001
|
|
Current smoker, n (%)
|
43 (53.8)
|
29 (20.1)
|
< 0.001
|
|
Comorbidities, n (%)
|
|
COPD
|
11 (8.4)
|
47 (29.4)
|
< 0.001
|
|
Congestive heart failure
|
11 (8.4)
|
21 (13.1)
|
0.22
|
|
Neurologic disease
|
15 (11.5)
|
37 (23.1)
|
0.012
|
|
Cancer
|
8 (6.1)
|
33 (20.6)
|
< 0.001
|
|
Renal disease
|
4 (3.1)
|
15 (9.4)
|
0.033
|
|
Liver disease
|
4 (3.1)
|
2 (1.3)
|
0.271
|
|
Symptoms, n (%)
|
|
Dyspnea
|
79 (68.7)
|
124 (83.8)
|
0.005
|
|
Dry cough
|
77 (58.8)
|
50 (31.3)
|
< 0.001
|
|
Headache
|
31 (66.0)
|
14 (32.6)
|
< 0.001
|
|
Muscle or joint pain
|
37 (64.9)
|
25 (51.0)
|
0.143
|
|
Nausea
|
36 (52.9)
|
28 (48.3)
|
0.538
|
|
Vomiting
|
28 (41.8)
|
20 (37.0)
|
0.686
|
|
Diarrhea
|
42 (53.2)
|
13 (15.5)
|
< 0.001
|
|
Confusion
|
24 (18.3)
|
32 (20.0)
|
0.718
|
|
Physical findings, median (IQR)
|
|
Heart frequency [BPM]
|
100 (82–112)
|
96 (83–111)
|
0.635
|
|
Systolic blood pressure (mmHg)
|
130 (118–145)
|
135.5 (119–151)
|
0.139
|
|
Diastolic blood pressure (mmHg)
|
73 (65–81)
|
75.5 (67–83)
|
0.111
|
|
Body temperature (°C)
|
39
(37.8–39.7)
|
38.4 (37.5–39.1)
|
0.002
|
|
CURB-65 [score 0–5], median (IQR)
|
1 (0–2)
|
2 (1–2)
|
0.016
|
|
Previous antibiotic treatment, n (%)
|
39 (33.6)
|
42 (26.8)
|
0.226
|
|
Laboratory findings, median (IQR)
|
|
Urea (mmol/L)
|
7.1 (5.5–11.4)
|
7.2 (5.0–9.1)
|
0.333
|
|
Creatinine (mc mol/L)
|
101 (80–131)
|
88 (66–108)
|
< 0.001
|
|
Sodium (mmol/L)
|
132 (129–135)
|
136 (133–138)
|
< 0.001
|
|
Potassium (mmol/L)
|
3.9 (3.5–4.2)
|
3.9 (3.6–4.3)
|
0.186
|
|
Bilirubin (µmol/L)
|
12 (8–19)
|
13 (8–16)
|
0.628
|
|
ASAT (IU/L)
|
49 (33–103)
|
26 (19–35)
|
< 0.001
|
|
ALAT (IU/L)
|
36 (24–67)
|
19 (13–29)
|
< 0.001
|
|
LDH (IU/L)
|
465 (324–609)
|
198 (168–238)
|
< 0.001
|
|
AP (IU/L)
|
79 (69–115)
|
82 (67–113)
|
0.242
|
|
GGT (IU/L)
|
47 (30–79)
|
37 (24–67)
|
0.034
|
|
C-reactive protein (mg/L)
|
317 (244–390)
|
162 (77–260)
|
< 0.001
|
|
Hemoglobin (mmol/L)
|
8.3 (7.8–9.1)
|
8.1 (7.3–8.9)
|
0.067
|
|
Platelets (× 109/L)
|
204 (156–249)
|
221 (179–293)
|
0.002
|
|
White blood cell count (× 109/L)
|
13 (10–17)
|
13 (10–18)
|
0.377
|