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Table 2 Comparison of positive results and agreement among mNGS and CMTs in immunosuppressed patients

From: Diagnostic value of metagenomic next-generation sequencing of bronchoalveolar lavage fluid for the diagnosis of suspected pneumonia in immunocompromised patients

Group NGS-positivea NGS-negative Total no Kappa, agreement
CMT-positive 22 3 25 0.121, 51.6%
CMT-negative 26 9 35  
Total no 48 12 60  
  1. mNGS metagenomic next-generation sequencing, CMTs conventional microbiological tests
  2. aPositive: patients with a positive microbiological diagnosis