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Table 3 Cox regression analysis of the demographic and clinical factors associated with mortality due to SARS-CoV-2 infection

From: Mortality among Italians and immigrants with COVID-19 hospitalised in Milan, Italy: data from the Luigi Sacco Hospital registry

  HR 95% CI p-value AHRa 95% CI p-value
Age (per 1 year more) 1.05 1.04–1.06  < 0.0001 1.07 1.06–1.08  < 0.0001
Males vs females 1.17 0.90–1.50 0.234 1.41 1.08–1.85 0.011
Time from symptoms onset (per 1 day more) 1.00 0.98–1.02 0.823 0.99 0.97–1.01 0.464
Non Italians vs Italians 0.43 0.30–0.63  < 0.0001 1.04 0.70–1.55 0.831
Obesityb YES vs NO 1.38 1.05–1.81 0.021 1.67 1.25–2.22  < 0.001
Moderate vs Mild COVID-19c 2.29 1.11–4.75 0.026 2.05 0.98–4.27 0.056
Severe vs Mild COVID-19c 3.98 1.92–8.29  < 0.001 3.84 1.82–8.09  < 0.001
Critically vs Mild COVID-19c 7.56 3.70–15.46  < 0.0001 8.59 4.12–17.88  < 0.0001
  1. HR hazard ratio, CI confidence interval
  2. aAdjusted for age, biological sex, time from symptoms onset, obesity and disease severity at hospital admission
  3. bObesity defined as body mass index of ≥ 30 points [17]
  4. cWHO disease severity classification [18]: mild = mild clinical symptoms, no imaging signs of pneumonia; moderate = fever, cough, dyspnea or other symptoms, imaging signs of pneumonia; severe = any of respiratory distress with a respiratory rate (RR) of ≥ 30 breaths per minute; resting oxygen saturation in air ≤ 93%; PaO2 / FiO2 ≤ 300 mmHg); critical = any of respiratory failure requiring mechanical ventilation; shock; any other organ failure needing intensive care