Fig. 2 | BMC Genomics

Fig. 2

From: Identification of novel genes involved in neutral lipid storage by quantitative trait loci analysis of Saccharomyces cerevisiae

Fig. 2

Analysis of segregants from crossing BY4741 with AWRI1631. a: Frequency distribution of fluorescence intensity of 2288 F1 segregants. The segregants with lower fluorescence than the BY4741 parental strain are shown in blue, the segregants with higher values than the AWRI1631 parental strain in red, and the segregants with intermediate intensity are depicted in gray. The frequencies of alleles that are beneficial for high NL content are shown for a subset of 43 out of the 60 segregants with the highest FI. b: WGS data of a section of chromosome XII, including the PIG1 peak (see Fig. S1 for the analysis of all chromosomes). The figure shows the median ratios between the frequencies of BY4741 and AWRI1631 parental strain-derived SNVs in the X-QTL analysis. Red points: selected subpopulation with high [NL]. Gray points: non-selected population with average [NL]. Each point shows a median AWRI1631:BY4741 ratio for all SNVs in a window of 10,000 bp. Black points: difference between the populations: higher abundance of the red than of the gray signal indicates that this region is enriched for AWRI1631 sequences in the population with high NL content. The gap in the signal marks a region derived exclusively from the BY4741 parent, i.e. a region with no SNVs calls relative to the BY4741 variant calling reference. Shading denotes the parental origin of the genomic region in the F7 generation of the backcrossing experiment selecting for high NL content (BY4741 – blue; AWRI1631 – red) in the BY lineage (upper ribbon) and in the AWRI lineage (lower ribbon)

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