Fig. 4 | Cancer Nanotechnology

Fig. 4

From: Targeting BMI-1 with PLGA–PEG nanoparticle-containing PTC209 modulates the behavior of human glioblastoma stem cells and cancer cells

Fig. 4

Cytotoxic effects of Nano-PTC209 on glioblastoma stem-like cells (GSCs) and U87MG cells were assessed by the MTT assay. a Representative phase-contrast images show the inhibitory effects of PTC209 and Nano-PTC209 on GSCs after 24 h. Bar diagrams show the half-maximal inhibitory concentration (IC50) value of PTC209 and Nano-PTC209, which was measured after 24 and 48 h treatment with different concentrations of the drugs. b Phase-contrast images of U87MG cells following 24 h treatment with Nano-PTC209. The IC50 values of Nano-PTC209 on U87MG cells are shown. The data are presented as means ± SD. ***P < 0.001

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