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Breast Cancer Research

, 5:E1 | Cite as

Erratum to: Functional and molecular characterisation of mammary side population cells

  • Azra J Alvi
  • Helen Clayton
  • Chirag Joshi
  • Tariq Enver
  • Alan Ashworth
  • Maria d M Vivanco
  • Trevor C Dale
  • Matthew J Smalley
Erratum

Correction

It has been brought to our attention that there was an inaccuracy in the above article [1]. In the discussion section the authors state that "One of the assumptions underlying mammary transplant studies is that mammary outgrowths at limiting dilution are clonal (14,000–20,000 cells per cleared fat pad)" and they attribute this to reference 21 "Smith GH: Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype. Breast Cancer Res Treat 1996, 39:21–31" [2]. In the paper by Smith no claim of clonality is made, rather it is stated that it is not known whether the simultaneous development of both lobular and ductal phenotypes indicates cooperative interaction between the two epithelial progenitors or signals the presence of a third progenitor type capable of producing both ductular and lobular committed daughters. It is, therefore, incorrect that the assumption of clonality based on limiting dilution has been attributed to Gilbert Smith.

References

  1. 1.
    Alvi A, Clayton H, Joshi C, Enver T, Ashworth A, Vivanco MdM, Dale TC, Smalley MJ: Functional and molecular characterisation of mammary side population cells. Breast Cancer Res. 2003, 5: R1-R8. 10.1186/bcr563.CrossRefPubMedGoogle Scholar
  2. 2.
    Smith GH: Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype. Breast Cancer Res Treat. 1996, 39: 21-31.CrossRefPubMedGoogle Scholar

Copyright information

© BioMed Central Ltd 2003

Authors and Affiliations

  • Azra J Alvi
    • 1
  • Helen Clayton
    • 1
  • Chirag Joshi
    • 2
  • Tariq Enver
    • 2
  • Alan Ashworth
    • 1
  • Maria d M Vivanco
    • 1
  • Trevor C Dale
    • 3
  • Matthew J Smalley
    • 3
    • 4
  1. 1.Breakthrough Toby Robins Breast Cancer Centre, Institute of Cancer ResearchLondonUK
  2. 2.Section of Gene Function and Regulation, Institute of Cancer ResearchLondonUK
  3. 3.Section of Cell and Molecular Biology, Institute of Cancer ResearchLondonUK
  4. 4.Current address: Division of Molecular GeneticsNetherlands Cancer InstituteAmsterdamThe Netherlands

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