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Breast Cancer Research

, 10:P35 | Cite as

Breast tomosynthesis in practice

  • I Andersson
Oral presentation

Keywords

Breast Cancer Dense Breast Angular Range Projection Image Digital Mammography 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

One of the factors limiting the sensitivity of conventional mammography (analogue and digital) is the obscuring effect of dense breast tissue overlying and underlying a tumor. This problem should be reduced by a tomographic technique. Tomosynthesis implies acquiring multiple projection images over a certain angular range with mathematical reconstruction of slices parallel to the detector plane. This technique is made possible by the recent development of digital detectors with high efficiency, which are capable of acquiring low-dose images with fast read-out and minimal image lag.

Within our group, optimization studies of tomosynthesis have been performed regarding factors such as angular range, number of projection images, data collection mode, and so on.

Tomosynthesis has also been under clinical evaluation in our institution for about 2 years. We have analyzed a series of breast cancer patients selected on the basis of difficult two-dimensional mammograms, and graded the visibility of the malignancies on two-dimensional as well as on three-dimensional mammograms. Furthermore, we have classified the mammograms according to the BIRADS Breast Imaging Reporting and Data System.

The results have shown a significantly better visibility and more accurate BIRADS classification with tomosynthesis. Accordingly, the results suggest that tomosynthesis is a more sensitive technique for the detection of breast cancer than conventional digital mammography. Further studies of the sensitivity and specificity are underway.

We believe that tomosynthesis will play an important role in the detection and diagnosis of breast cancer in the future.

Copyright information

© BioMed Central Ltd 2008

Authors and Affiliations

  • I Andersson
    • 1
  1. 1.Department of Diagnostic RadiologyUniversity Hospital of Malmö MASMalmöSweden

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