The migration of leukocytes to sites of infec-tion and tissue injury is a primary defence mechanism. When localized at the infection site polymorphonuclear leucocytes phagocy-tose bacteria and other foreign particles. The leukocyte is also of interest as a source of inflammation mediators e.g. metabolites of arachidonic acid (Simmons et al 1983).
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Luthman, J., Bengtsson, B. & Korpe, C. The Effect of Oxytetracycline on Leukocyte Migration into Inflammatory Exudate. Acta Vet Scand 29, 505–507 (1988). https://doi.org/10.1186/BF03548649