The Effects of Praziquantel on the Monogenean Gill Parasite Pseudodactylogyrus Bini


The anthelminthic Praziquantel is found to be effective against trematodes and cestodes (for a comprehensive review of various aspects of this drug, see Andrews et al. 1983). Praziquantel has been reported to affect fish cestodes (Pool et al. 1984, Moser et al. 1986, Ward et al. 1986), fish digeneans (Bylund & Sumari 1981) and fish monogeneans (Schmahl & Mehlhorn 1985). Therefore Praziquantel could be a potential drug against Pseudodactylogyrus spp. parasitizing the gills of eels. Infections with these monogeneans cause problems in eel farms (Ogawa & Egusa 1976, Egusa 1979, Chan & Wu 1984, Mellergaard & Dalsgaard 1986). Köhler & Bachmann (1978) tested the effect of Praziquantel on the activity of succinate dehydrogenase and NADH-diaphorase (NADH-oxidase) from Ascaris suum and reported that the latter enzyme was inhibited by Praziquantel.

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  1. Andrews Ρ, Thomas Η, Pholke R, Seubert J: Praziquantel. Med. Res. Rev. 1983,3, 147–200.

    CAS  Article  Google Scholar 

  2. Bylund G, Sumari O: Laboratory tests with Droncit against Diplostomiasis in rainbow trout Salmo gairdneri Richardson. J. Fish Dis. 1981,4, 259–264.

    Article  Google Scholar 

  3. Chan Β, Wu B: Studies on the pathogenicity, biology and treatment of Pseudodactylogyrus for the eels in fishfarms. Acta zool. Sin. 1984,30, 173–180.

    Google Scholar 

  4. Egusa S: Notes on the culture on the European eel (Anguilla anguilla L.) in Japaneese eel farming ponds. Rapp. P. v. Reun. Cons. Int. Explor. Mer. 1979,174, 51–58.

    Google Scholar 

  5. Kohler P, Bachmann R: The effects of the antiparasitic drugs Levamisole, thiabendazole, praziquantel, and chloroquine on mitochondrial electron transport in muscle tissue from Ascaris suum. Mol. Pharmacol. 1978,14, 155–163.

    CAS  PubMed  Google Scholar 

  6. Mehler J: Neues auf dem Gebiet der Fischkrankhei–ten. (News from the area of fish diseases). Fischer & Teichwirt. 1987,1, 8–11.

    Google Scholar 

  7. Mellergaard S, Dalsgaard I: Disease problems in da–nish eel farms. Proc. 2nd Intern. Colloq. Pathol. Marine Aquae. 7–11 sept. Porto. 1986, p. 113.

    Google Scholar 

  8. Moser M, Sakanari J, Heckmann R: The effects of Praziquantel on various larval and adult parasites from freshwater and marine snails and fish. J. Parasit. 1986,72, 175–176.

    CAS  Article  Google Scholar 

  9. Ogawa K, Egusa S: Studies on eel Pseudodactylogy-rosis - I. Morphology and classification of three dactylogyrids with a proposal of a new species, Pseudodactylogyrus microrchis. Bull. Jap. Soc. Sci. Fish. 1976,42, 395–404.

    Article  Google Scholar 

  10. Pool D, Ryder K, Andrews C: The control of Both–riocephalus acheilognathi in grass carp, Ctenop–haryngodon idella, using Praziquantel. Fish. Mgmt. 1984,15, 31–33.

    Google Scholar 

  11. Schmahl G, Mehlhorn H: Treatment of fish parasites. 1. Praziquantel effective against Monogenea (Dactylogyrus vastator, Dactylogyrus extensus, Diplozoon paradoxum). Z. Parasitenkd. 1985,71, 727–737.

    CAS  PubMed  Google Scholar 

  12. Ward S M, Allen J M, McKeer G: Action of praziquantel on Grillotia erinaceus metacestodes (Ce–stoda: Trypanorhyncha) in vitro. Parasitology 1986,93, 133–142.

    CAS  Article  Google Scholar 

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Laboratory facilities during this study was kindly provided by S. Mellergaard, Danish Institute for Fishery and Marine Research, Fish Disease Laboratory. J. Bjerregaard, Department of Pharmacy, Royal Veterinary and Agricultural University Denmark is thanked for valuable discussions.

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Correspondence to Kurt Buchmann.

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Buchmann, K. The Effects of Praziquantel on the Monogenean Gill Parasite Pseudodactylogyrus Bini. Acta Vet Scand 28, 447–450 (1987).

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  • Pseudodactylogyrus bini
  • Praziquantel
  • succinate dehydrogenase
  • NADH–diaphorase