Embryonic death in pigs caused by unbalanced karyotype

Fosterdöd hos svin till följd av obalanserad kromosomuppsättning

Abstract

A landrace boar being heterozygous for a translocation has been used in 43 matings to 30 sows. Compared to a normal boar which also served part of the same sow group the defect boar had a by 30 % reduced fertility. Five different types of unbalanced karyotypes were detected in fetuses sired by the translocation heterozygote. Since no unbalanced karyotype was to be found postnatally in 111 offspring, all defect karyotypes seem to be lethal at the embryonic stage. Forty-one % of the postnatally investigated cases had the same translocation as the father.

Sammanfattning

En lantrasgalt som var heterozygot för en translokation har använts i 43 parningar med 30 suggor. I jämförelse med en normalgalt, som delvis använts till samma suggor, hade den förstnämnda galten en med drygt 30 % reducerad fertilitet. Fem olika typer av obalanserade kromosomuppsättningar påvisades hos foster efter translokationsheterozygoten. Eftersom ingen obalanserad karyotyp påträffades hos 111 avkomlingar efter födelsen, torde samtliga defekta karyotyper ha dött på fosterstadiet. 41 % av de postnatalt undersökta individerna hade samma translokationsdefekt som fadern.

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Correspondence to A. Åkesson.

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Åkesson, A., Henricson, B. Embryonic death in pigs caused by unbalanced karyotype. Acta Vet Scand 13, 151–160 (1972). https://doi.org/10.1186/BF03548568

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