Aspergillus fumigatus is an important agent of mycotic infection in cattle and a potent source of antigens. However, the efficacy of serological diagnosis of aspergillosis in cattle remains controversial. Corbel (1972) and Knudtson et al. (1974) considered a precipitin assay useful as a supplementary test in the diagnosis of mycotic abortion, whereas Wiseman et al. (1984) found the specificity too low to justify its routine use. We have studied 1) the antibody response to the catalase antigen of A. fumigatus in experimentally infected cattle and 2) the prevalence of catalase antibodies and A. fumigatus precipitins in healthy and diseased cattle. The aim was to ascertain how far detection of antibodies to a defined fungal antigen can contribute to the often difficult diagnosis of mycosis.
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Corbel M J: The serological response to Aspergillus fumigatus antigens in bovine mycotic abortion. Brit Vet. J. 1972,128, lxxiii–lxxv.
Knudtson W U, Kirkbride CA, Thurston JR: Bovine mycotic abortion: serology as an aid in diagnosis. Proceedings of the American Association of Veterinary Laboratory Diagnosticians, 17th Annual Meeting, October 1974, 299–303.
Schønheyder H, Andersen P, Munck Petersen J C: Rapid immunoelectrophoretic assay for detection of serum antibodies to Aspergillus fumigatus catalase in patients with pulmonary aspergillosis. Eur. J. Clin. Microbiol. 1985, 4, 299–303.
Schønheyder H, Andersen P, Stenderup A: Serum antibodies to Aspergillus fumigatus in patients with pulmonary aspergillosis detected by immunofluorescence. Acta Pathol. Microbiol. Immunol. Scand. Sect. B 1982, 90, 273–279.
Wiseman A, Dawson C O, Selman IE: The prevalence of serum precipitating antibody to Aspergillus fumigatus in adult cattle in Britain. J. Comp. Pathol. 1984, 94, 535–552.
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Schønheyder, H., Jensen, H.E. Serum Antibodies to the Catalase Antigen of Aspergillus fumigatus in Cattle. Acta Vet Scand 29, 143–144 (1988). https://doi.org/10.1186/BF03548405