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EJNMMI Physics

, 2:A77 | Cite as

The potential of TOF PET-MRI for reducing artifacts in PET images

  • Andrei Iagaru
  • Ryogo Minamimoto
  • Craig Levin
  • Amid Barkhodari
  • Mehran Jamali
  • Dawn Holley
  • Zaharchuk Greg
Open Access
Meeting abstract

Keywords

Image Quality Quality Score Oncologic Patient High Image Quality High Image 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Here we evaluated the potential of TOF PET/MRI to reduce various PET image artifacts, by comparing the images to non-TOF PET/MRI, TOF PET/CT and non-TOF PET/CT.

Methods and materials

All patients underwent a single-injection of FDG, followed first by PET-CT and subsequently by PET-MRI scan. The PET/CT exams were performed using a GE Discovery 690 PET/CT scanner. The PET/MRI images were acquired on a GE Signa PET/MRI scanner. All PET images were reconstructed with and without the TOF data. Visual analysis of these series was performed for dental metal / breathing artifcats and 3) artifacts caused by high excretion of FDG in the bladder. PET image quality was evaluated using a 3-point scale (1 - clinically significant artifact; 2 – non clinically-significant artifact; and 3 - no artifact). Data from 18 oncologic patients (mean ± SD age: 55 ± 10 years; female 7, male 11) were used. The average scores of TOF PET/MRI, non-TOF PET/MRI, TOF PET/CT and non-TOF PET/CT for dental artifacts were 3.0, 2.8, 2.4 and 2.3, respectively; for breathing artifacts were 3.0, 2.5, 2.5 and 2.3, respectively; and for pelvic artifacts were 2.9, 1.6, 2.1 and 1.4, respectively. TOF PET/MRI had the highest image quality scores among the 4 series of PET data analyzed for these types of artifacts. TOF PET/MRI showed promising results in reduction of various PET artifacts in this cohort, when compared to non-TOF PET/MRI, TOF PET/CT and non-TOF PET/CT. This may be due to the better timing resolution (<400 ps) for the PET/MR system compared to the PET/CT system (>600 ps).

Copyright information

© Iagaru et al; licensee Springer. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Authors and Affiliations

  • Andrei Iagaru
    • 1
  • Ryogo Minamimoto
    • 1
  • Craig Levin
    • 1
  • Amid Barkhodari
    • 1
  • Mehran Jamali
    • 1
  • Dawn Holley
    • 1
  • Zaharchuk Greg
    • 1
  1. 1.Stanford UniversityUSA

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