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Slow continuous dialysis treatment in septic shockcaused by acinetobacter

  • S Sen
  • H Akdam
  • SB Ozturk
  • A Soyder
Open Access
Poster presentation
  • 215 Downloads

Keywords

Mechanical Ventilation Septic Shock Renal Replacement Therapy Continuous Renal Replacement Therapy Acinetobacter Baumannii 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Background/Purpose

Acinetobacter baumannii blood stream infection has a high mortality rate of 50-60% % for critical patients treated in ICUs [1]. The effect of continuous venovenous hemodiafiltration (CVVHDF) is described in patients with septic shock undergoing major abdominal surgery in this retrospective case series.

Methods

Septic shock (acinetobacter baumannii) and acute renal injury (AKI) was found in 14 of the 53 patients undergoing major abdominal surgery (colon resection, Whipple). CVVHDF in 6 patients, the intermittent hemodialysis (HD) was performed in 8 patients diagnosed with septic shock.

Results

In CVVHF group only 1 patient, in the intermittent HD group 2 patients had died. The duration of mechanical ventilation was 32.3 ± 3.8 days in the HD group, while was 23.8 ± 5 .4 day in CVVHDF group. 3 patients who died had diabetes mellitus. APACHE II scores were significantly higher in the two groups. Repetitive operation due to anastomotic leakage was made in CVVHDF group 3 patients and in HD group 4 patients.

Discussion and Conclusion

Factors that increase mortality in patients with acinetobacter sepsis: reoperation, high APACHE II scores, mechanical ventilation, diabets mellitus and acute renal failure [1]. Continuous renal replacement therapy has the advantage of achieving a more stable haemodynamic situation and an easier volume management compared to intermittent HD. Removal of cytokines is also provided easier with CVVHDF [2]. It is concluded that mortality rate and the duration of mechanical ventilation was less in patients undergoing CVVHDF in present study.

References

  1. 1.
    Int J Infect Dis. 2014, 22: 25-30.Google Scholar
  2. 2.
    Int Urol Nephrol. 2014, 46: 2009-2014. 10.1007/s11255-014-0747-5.Google Scholar

Copyright information

© Sen et al.; 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Authors and Affiliations

  • S Sen
    • 1
  • H Akdam
    • 2
  • SB Ozturk
    • 3
  • A Soyder
    • 4
  1. 1.Adnan Menderes University Medical FacultyAnesthesiology and ReanimationAydinTurkey
  2. 2.Adnan Menderes University Medical FacultyNephrologyAydinTurkey
  3. 3.Adnan Menderes University Medical FacultyInfection DiseasesAydinTurkey
  4. 4.Adnan Menderes University Medical FacultyGeneral SurgeryAydinTurkey

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