Epidemiology of Sepsis in Germany: Incidence, Mortality And Associated Costs of Care 2007-2013
- 563 Downloads
KeywordsSevere Sepsis Hospital Statistics Diagnosis Related Group Death Statistics Health Care Budget
Sepsis is a life-threatening condition following acute infections. It is a global public health disaster. in Germany, epidemiological data on incidence, mortality and costs of sepsis is scarce.
To assess the development of sepsis incidence, mortality and costs of care in Germany.
We performed a nation-wide analysis of coded sepsis cases from 2007 to 2013 based on German Diagnosis Related Groups Statistics, Hospital Statistics, and Causes of Death Statistics. Sepsis cases were identified by a) clinical sepsis codes for sepsis, severe sepsis and septic shock (R65.0!, R65.1!, R57.2, respectively, as secondary diagnosis) from the DRG Statistics and b) microbiological sepsis codes (A02.1, A20.0, A20.7, A21.7, A22.7, A24.1, A26.7, A28.2, A32.7, A39.2, A39.3, A39.4, A39.1,, A40.-, A41.-, A42.7, A48.3, B00.7, A54.8, B37.7, B37.6, B49, A49.9, P36.-, O75.3, O85, R57.2 as primary diagnosis) from the Hospital Statistics and Causes of Death Statistics. Costs were estimated based on data issued by the German Federal (Social) Insurance Office.
The incidence of sepsis in Germany is higher than expected and on the rise. Demographical change and the advances in medical care and intensive care in particular may have contributed to this increase of sepsis cases, as well as better awareness and reimbursement incentives may have influenced coding practices. Mortality has not declined substantially. Transsectoral quality measures in other countries have contributed to a considerable decrease of mortality and similar measures are urgently needed in Germany. Monitoring of sepsis indices should become a regular feature of the Federal Health Monitoring and Hospital Statistics reporting.
The CSCC is funded by the German Federal Ministry of Education and Research (BMBF), Germany, FKZ: 01EO1002.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.