Medical care and long-term treatment of patients with schizophrenia: ethical concerns

  • Frederico Simões do Couto
Open Access
Meeting abstract


Hypertension Obesity Hepatitis Osteoporosis Schizophrenia 
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Despite the improvement in mental health care that has occurred in the last decades, the mortality risk in patients with schizophrenia has not been changed, and there was even an increase in the mortality of these patients when compared to the general population. The main causes for this increased mortality are somatic diseases, especially diabetes, hypercholesterolemia, hypertrygliceridemia, cardiovascular diseases (including arterial hypertension), obesity, HIV infection/AIDS, hepatitis C and osteoporosis [1]. The link between second generation antipsychotics and cardiovascular risk factors has raised questions on their overall safety, and these concerns are even more important if patients are on compulsory treatment. Furthermore, at least half of patients suffering from schizophrenia have one co-morbidity not diagnosed or wrongly diagnosed [2]. In a sample of 476 community patients suffering from schizophrenia, we found rates of diagnosed hypertension of 6,9%, hypercholesterolemia of 9,0%, hypertrigliceridemia of 6,3%, and diabetes of 4,2%. Not only these figures are lower than in other large studies, but also apparently only 12 to 30% of the patients presenting these disorders were being treated for these conditions [3]. Barriers to recognition and management of physical diseases in patients with schizophrenia are related both to health care providers and to patient/disease. Acute admission could be a target for the screening and treatment of these disorders, and we tried to find a screening protocol for this situation. Acutely ill patients have higher rates of infections and liver abnormalities, but lower rates of hypercholesterolemia [4]. In our sample more than 80% of patients with schizophrenia are retired or unemployed. Resources are scarce, and their allocation to these patients can prevent the access of people suffering from other disorders to the care they need.


  1. 1.
    Saha S, et al: A systematic review of mortality in schizophrenia: is the differential mortality gap worsening over time?. Arch Gen Psychiatry. 2007, 64 (10): 1123-31. 10.1001/archpsyc.64.10.1123.CrossRefPubMedGoogle Scholar
  2. 2.
    Muir-Cochrane E: Medical co-morbidity risk factors and barriers to care for people with schizophrenia. Journal of psychiatric and mental health nursing. 2006, 13 (4): 447-52. 10.1111/j.1365-2850.2006.01002.x.CrossRefPubMedGoogle Scholar
  3. 3.
    Simões do Couto F: The characterization of a Portuguese population of outpatients with schizophrenia, and their therapeutical management, in the European context.Google Scholar
  4. 4.
    Teixeira J, et al: Which blood analysis should be requested to patients with schizophrenia when hospitalized for acute psychosis?. 17th EPA European Congress of Psychiatry, Lisbon, January 24-28. 2009Google Scholar

Copyright information

© do Couto; licensee BioMed Central Ltd. 2009

This article is published under license to BioMed Central Ltd.

Authors and Affiliations

  • Frederico Simões do Couto
    • 1
  1. 1.Neuroscience Department of the Institute of Molecular Medicine, Lisbon, and Department of PsychiatryHospital de Santa Maria and Faculty of Medicine of LisbonPortugal

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