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Retrovirology

, 6:O5 | Cite as

Small RNA-mediated control of retrotrotransposons in Drosophila

  • Severine Chambeyron
  • Christine Brun
  • Alain Bucheton
  • Alain Pélisson
  • Vincent Serrano
Open Access
Oral presentation
  • 766 Downloads

Keywords

Infectious Disease Cancer Research Somatic Cell Important Variation Small RNAs 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

In the Drosophila ovary, the I-element (a NLR retrotransposon) and gypsy are both controlled by piRNAs (small RNAs associated with Piwi-like proteins); but there are important variations on this common theme, according to the cell lineage where it operates: the germline (for the I-element) versus the ovarian somatic cells (for gypsy). We are taking advantage of these differences to study the piRNA biogenesis, the epigenetic effects of the maternal transmission of piRNAs and the mechanism of piRNA-mediated regulation.

Copyright information

© Chambeyron et al; licensee BioMed Central Ltd. 2009

This article is published under license to BioMed Central Ltd.

Authors and Affiliations

  • Severine Chambeyron
    • 1
  • Christine Brun
    • 1
  • Alain Bucheton
    • 1
  • Alain Pélisson
    • 1
  • Vincent Serrano
    • 1
  1. 1.IGH (CNRS)MontpellierFrance

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