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Retrovirology

, 3:P17 | Cite as

Phylogeny of HTLV-I isolates from groups with risk antecedents for human retrovirus infections in Argentina

  • Maria Emilia Eirin
  • Carolina Berini
  • María Angeles Pando
  • Maria Avila
  • Horacio Salomon
  • Mirna Biglione
Open Access
Poster presentation
  • 1.2k Downloads

Keywords

Infectious Disease Cancer Research Package Program Parsimony Tree Positive Individual 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Background

HTLV-I infection shows an ethnic-geographic restriction being naturally endemic among aborigines from the Northwest. At-risk populations are also infected with HTLV-I. Cosmopolitan subtype (a) including subgroups A, B and C has been described previously in our country.

Materials and methods

35 HTLV-I samples were analyzed including 3 MSM, 6 FSW (1 from Peru and 3 from Salta), 13 BD (1 Japanese descendent), 5 HAM/TSP (3 from Peru) and 8 HIV positive individuals. The rest were from Buenos Aires (BA) city. LTR regions were amplified by n-PCR. Neighbor-joining and Parsimony trees were performed using Phylip package program.

Results

32 samples were identified as the Cosmopolitan subtype a, subgroup A. One HAM/TSP aA sample from BA was more distantly related to the rest of the aA samples. Furthermore, 2 samples (1 Peruvian HAM/TSP and 1 Japanese BD from BA) clustered with the previously described Br4, Br9 (from Brazil) and B13.Peru.

Conclusion

The majority of the circulating HTLV-I strains in Argentina belonged to the subgroup A. The finding of these 2 samples, clustering separately from any other known HTLV-I subgroup, agrees with previous suggestions of a possible divergent subgroup within subtype a.

Copyright information

© Eirin et al; licensee BioMed Central Ltd. 2006

This article is published under license to BioMed Central Ltd.

Authors and Affiliations

  • Maria Emilia Eirin
    • 1
  • Carolina Berini
    • 1
  • María Angeles Pando
    • 1
  • Maria Avila
    • 1
  • Horacio Salomon
    • 1
  • Mirna Biglione
    • 1
  1. 1.National Centre Reference for AIDSSchool of MedicineBuenos AiresArgentina

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