CMR techniques and findings in children with myocarditis: a multicenter retrospective study
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KeywordsEjection Fraction Congenital Heart Disease Myocarditis Late Gadolinium Enhancement Regional Wall Motion Abnormality
CMR is increasingly used to diagnose myocarditis in adults but its use in pediatric-age pts is not well established. We sought to describe the clinical presentation, CMR imaging protocols, CMR findings, and outcomes in a multicenter cohort of children with myocarditis.
A retrospective review was conducted among 12 institutions from 3 countries. All pts meeting the following criteria were included: 1) age < 21 years, 2) ultimate clinical diagnosis of myocarditis by the referring physicians, 3) CMR examination within 30 days of presentation, and 4) no congenital heart disease. Clinical data and test results, including CMR findings, were abstracted from the medical record.
This is the largest study to date describing the CMR findings in children with myocarditis. The CMR techniques used, from most to least common, were LGE, T2W, FPP, and EGE. Abnormalities were most often seen with LGE followed by T2W, EGE, and FPP. There was significant practice variation in the CMR protocol between institutions. The information from this study should be useful in planning a prospective study to evaluate the diagnostic and predictive performance of CMR in children with suspected myocarditis.
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