Advertisement

Utility of cardiac magnetic resonance imaging in identifying the potential structural heart disease for ventricular arrhythmia before ablation

  • Yucheng Chen
  • Jian Jiang
Open Access
Poster presentation
  • 420 Downloads

Keywords

Ventricular Tachycardia Cardiac Magnetic Resonance Ventricular Arrhythmia Late Gadolinium Enhancement Cardiac Magnetic Resonance Imaging 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Background

Cardiac magnetic resonance imaging (CMR) is a powerful tool to identify the arrhythmia substrate in patients with ischemic or non-ischemic cardiomyopathy. However, the performance and diagnostic yield of CMR in pre-ablation evaluation for ventricular arrhythmia in patients without known structural heart disease was still unknown. In the present study, we sought to investigate the performance of CMR in identifying the potential structural heart disease or substrate for ventricular arrhythmia in pre-ablation patients.

Methods

CMR was performed in a series of consecutive patients (average age 45.8±16.9 years) with premature ventricular contraction or paroxysmal ventricular tachycardia referred for trans-catheter ablation. None of the patients had any known structural heart disease. CMR protocol included regular cine, rest perfusion and late gadolinium enhancement imaging. CMR image was interpreted by two experienced experts who were blinded to the echocardiography findings and clinical diagnosis.

Results

The average left ventricular ejection fraction of the whole cohort was 54.9±11.1% and right ventricular ejection fraction was 45.6±15.6%. there was no significant difference in LVEDVI, LVESVI, LVMASSI,LVEF, RVEDVI, RVESVI and RVEF between patients with PVC and VT. There was 17/40(42.7%) abnormal global or regional wall motion findings by CMR cine. myocardial late gadolinium enhancement (LGE) was found in 10/40 (25%) cases. The cumulative abnormalities rate was 45% through CMR, whereas abnormal findings was only confirmed in 6/40(15%) in the same group of patients. In addition, in patients with LGE, RVEDVI, RVESVI and RVEF were significantly decreased than the patients without LGE.

Conclusions

CMR was a powerful tool to identify the potential structural heart disease in patients with ventricular arrhythmia before ablation. Comprehensive CMR examination appeared to be more sensitive than echocardiography in detecting structural abnormalities in patients with ventricular tachycardia without known cardiomyopathy, before ablation therapy is planned.

Funding

national science foundation of China (NSFC) 81271513
Table 1

Abnormalities of pre-ablation CMR in patients with ventricular arrhythmia

 

Total (percent)

PVC

VT

Number

40

12

28

Echo

   

normal

34(85%)

11(92%)

23(82.1%)

abnormal

6(15%)

1(8%)

5(17.9%)

CMR cine

   

normal

23(57.5%)

6(50%)

17(60.7%)

abnormal

17(42.5%)

6(50%)

11(39.3%)

late enhancement

   

normal

30(75%)

10(83.3%)

20(71.4%)

abnormal

10(25%)

2(16.7%)

8(28.6%)

CMR cumulative abnormalities

18(45%)

6(50%)

12(42.9%)

*Cine abnormalities including left and right ventricular global and/or regional wall motion abnormalities.CMR :cardiac magnetic resonance

Copyright information

© Chen and Jiang; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Authors and Affiliations

  • Yucheng Chen
    • 1
  • Jian Jiang
    • 1
  1. 1.West China HosptialChengduChina

Personalised recommendations