Single breathhold three-dimensional cardiac cine MRI with whole ventricular coverage and retrospective cardiac gating using kat ARC
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KeywordsCardiac Phase Spatiotemporal Correlation Center Acceleration Complete Cardiac Cycle 48ms Temporal Resolution
This work presents a kt acceleration method (kat ARC) for retrospective cardiac-gated 3D cardiac cine MRI. Our in-vivo results show that 3D cine images of the entire ventricle are obtainable within a single breathhold using highly accelerated kat ARC.
For quantitative volumetric assessments of cardiac function, 3D cine images depicting motion of the entire ventricle in a complete cardiac cycle are needed. However, due to limited acceleration capability, breathheld 3D cine MRI is not obtainable using conventional parallel imaging. Several kt-acceleration methods have demonstrated high-acceleration capability for dynamic MRI by exploiting spatiotemporal correlation [Tsao, MRM 2003; Huang, MRM 2005]. This study aims to investigate the feasibility of breathheld retrospective cardiac-gated whole-ventricle 3D cine MRI using kat ARC (k-adaptive-t Autocalibrating Reconstruction for Cartesian sampling [Lai, ISMRM 2009]).
Healthy volunteers were scanned on a GE 1.5T scanner with a 32-channel cardiac coil. 3D cine images were collected from a short-axis slab covering the entire ventricle (2.5×2.5mm2 in-plane resolution, 24 slices with 5mm thickness, 48ms temporal resolution). Each volunteer was scanned 3 times using different acceleration: A. Reference with 6× (~30 sec): 3×2 outer and 2×1 center acceleration; B. 8× (~20 sec): 4×2 outer and 3×1 center acceleration; C. 10× (~16 sec): 5×2 outer and 2×2 center acceleration. High acceleration images were compared with the reference image with regard to overall image quality and motion depiction.
Based on our in vivo results, single breathhold imaging of whole-ventricular cardiac motion is achievable using highly accelerated kat ARC. Future work will further optimize imaging parameters and sampling pattern to improve image quality at high acceleration and conduct clinical evaluations.
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