Independent respiratory navigators for improved 3D PSIR imaging of myocardial infarctions
KeywordsLate Gadolinium Enhancement Reference Image Motion Compensation Reference Volume Respiratory Navigator
Imaging was performed on a 3T system (Philips Healthcare, Best, The Netherlands) using a 32-channel cardiac array coil (InVivo, Gainsville FL). Phantoms: agar gel phantoms with varying T1 values were placed on a pneumatic motor that oscillated 20 mm in the antero-posterior direction every second. Animals: Under ACUC-approved protocol, six swine underwent 2 hr LAD occlusion. Imaging took place 4-25 weeks post-infarction and 10-3 min post double-dose injection of Magnevist (Schering, Germany). A 3D GRE sequence with 1.25x1.25x4 mm3 resolution and 2.5 min scan time ( assuming 100% gating efficiency) was used.
Figure 1 (c-j) compares PSIR and INPSIR. (c-d) images from moving agar gels demonstrate possible artifacts when no motion compensation is used for the reference images. Short-axis images from an infarcted swine model including reference image magnitude, single-coil phase and phase-sensitive reconstruction are shown. The phase reference image was improved with INPSIR (arrows) and navigator efficiency was not affected.
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