1044 High spatial and temporal resolution MRA (TWIST) in acute aortic dissection
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KeywordsAortic Dissection Temporal Resolution False Lumen Acute Aortic Dissection Contrast Agent Bolus
Endovascular treatment of descending thoracic and abdominal aortic dissection has emerged as an alternative to open surgery. In terms of endovascular aortic stent-graft placement planning, MRI appears to be particularly useful as it can provide a comprehensive pre-interventional diagnostic evaluation of the vascular aortic morphology. However, standard MRA techniques provided no information on flow and tissue perfusion. Until now sufficient temporal resolution and coverage for the assessment of aortic dissection could only be achieved scarifying spatial resolution, thus requiring an additional high resolution MR angiography. Our study aimed to evaluate the image quality and the diagnostic accuracy of a recently developed time-resolved 3D MR angiography technique (TWIST) combining high spatial and temporal resolution for the pre-interventional assessment of aortic dissection.
Twenty patients (mean age 58 y) with dissection of the descending thoracic and/or abdominal aorta underwent contrast-enhanced time-resolved 3D MR-angiography. All imaging was performed on a 1.5 T scanner (Avanto, Siemens, Medical Solutions, Erlangen, Germany). Following automatic injection of 5 ml Gadovist (Schering, Berlin, Germany) at 3 ml/sec, 15 consecutive coronal T1w 3D datasets (TR/TE 2.8/1.2 ms; FA 25°; slices 64; matrix 231 × 320; spatial resolution 1.9 × 1.6 × 2.1 mm3, effective temporal resolution 1.6 s) were acquired using the TWIST sequence and parallel imaging technique (GRAPPA; R = 2). For TWIST all k-space points are sorted according to their radial distance in k-space and the k-space is divided into a central region A and a peripheral region B. While region A is completely sampled for all 15 data sets, region B is undersampled by a factor of n to improve the temporal resolution. About 5 minutes following the time-resolved MRA, a conventional high spatial resolution MRA (0.1 mmol/kg Gadovist®) was acquired (breath hold 25 s) using a 3D spoiled gradient-echo sequence (TR/TE 3/0.97 ms, FA 25°, slices 72, matrix 289 × 384; voxel size 1.4 × 1.3 × 1.8 mm3). Both MR data sets were evaluated and compared for image quality and visualization of vascular details. A radiologist and an interventional cardiologist assessed the additional diagnostic information of the TWIST concerning contrast enhancement and tissue perfusion.
TWIST MRA is a robust technique that combining functional and morphological information. Thus the time-resolved TWIST MRA provides all information for treatment planning in patients suffering from acute aortic dissection.
This article is published under license to BioMed Central Ltd.