Acute hemodynamic effect of inhaled iloprost in pulmonary artery hypertension evaluated with echocardiography
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Doppler echocardiography is useful in the initial evaluation and long-term follow-up of patients with pulmonary artery hypertension. Aerosolised iloprost has been shown to reduce pulmonary pressure immediately after inhalation. We report the echocardiographic findings in a patient with severe pulmonary hypertension, before and after the inhalation of aerosolized iloprost. These findings illustrate the acute influence of iloprost in right and left ventricular hemodynamics and morphology. These findings were reproduced in subsequent echocardiographic evaluations.
KeywordsPulmonary Arterial Hypertension Doppler Echocardiography Iloprost Pulmonary Artery Hypertension Severe Pulmonary Hypertension
Additional file 3: Three-dimensional parasternal view before iloprost inhalation. Three-dimensional parasternal long axis view before iloprost inhalation showing a small left ventricle with increased eccentricity index. (AVI 9 MB)
Additional file 4: Three-dimensional parasternal view after iloprost inhalation. Three-dimensional parasternal long axis view after iloprost inhalation showing near normal morphology of both ventricles. (AVI 8 MB)
The findings that we describe showed the potential utility of echocardiography in the evaluation of the acute effects of drugs used in the treatment of pulmonary arterial hypertension.
Written informed consent was obtained for publication from the patient.
- 2.Burgess M, Bright-Thomas R, Ray S: Echocardiographic evaluation of right ventricular function. Eur J Echocardiography. 2002, 3: 252-262.Google Scholar
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