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Table 1 Changes in MASI scores of tested drugs in melasma patients

From: The treatment of melasma by silymarin cream

   MASI
Treatment Baseline After 1stweek After 2nd week After 3rd week After 4th week
G I: SM 7 mg/ml 17.1 ± 3.12 12.3 ± 2.3a 6.6 ± 2.4b 0.2 ± 1.72b 0b
G II: SM 14 mg/ml 16.5 ± 2.8 10.4 ± 1.2a 3.5 ± 1.4b 0b 0b
G III: Placebo 16.8 ± 3.2 16.8 ± 3.3c 16.8 ± 3.5c 17 ± 3.4c 17 ± 3.4c
  1. a p ≤ 0.01, b p ≤ 0.0001, c p ≥ 0.05.