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BMC Neuroscience

, 8:P41 | Cite as

Enhanced measured synchronization of unsynchronized sources: significance for brain recordings

  • Luis Garcia Dominguez
  • Richard Wennberg
  • Jose Luis Perez Velazquez
  • Ramon Guevara
Open Access
Poster presentation

Keywords

Animal Model Real Data Brain Activity Current Method Temporal Resolution 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

The analysis of synchronization, particularly phase locking, is being increasingly used in neuroscience to explore coordinated brain activity. The application of this methodology to magnetoencephalographic (MEG) and electroencephalographic (EEG) recordings would seem promising because these two recording techniques have great temporal resolution. However, current methods of synchronization analysis applied to raw MEG/EEG data may not be as physiologically sound as previously thought. In this work we present a model of brain activity based on random current dipoles that reproduces the main characteristics observed in measurements of real data synchronization, even when no synchronized activity is taking place among the sources. In particular, we show that the enhanced local synchronization, previously described in some studies of epileptic seizures, may result from the activity of only a few unsynchronized sources.

Copyright information

© Dominguez et al; licensee BioMed Central Ltd. 2007

This article is published under license to BioMed Central Ltd.

Authors and Affiliations

  • Luis Garcia Dominguez
    • 1
  • Richard Wennberg
    • 1
  • Jose Luis Perez Velazquez
    • 1
  • Ramon Guevara
    • 1
  1. 1.Hospital for Sick ChildrenUniversity of TorontoTorontoCanada

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