Interfacing neuroVIAS and NEST
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KeywordsBrain Region Neuronal Network Image Processing Method Large Scale Simulation Java Application
Our framework (neuroVIAS) integrates neuroimaging, brain-mapping, neuroanatomic ontologies and tracing-based connectivity data and allows to analyze these data in multiple modalities. Most of the data has been gathered from real brains, such as the information about connections between structures at different levels of resolution. These information include features like strength, inhibition or excitation. It is intended to use the collected data as an input for the simulation of neuronal networks with sophisticated simulation environments like NEST. As a starting point, a graphical user interface in neuroVIAS has been developed, that allows the specification of a simulation according to NEST guidelines based on filtering mechanisms of the rat connectome.
In this contribution we present the interface that allows the definition of parameters and adaption of new parameters for simulations in NEST. This open framework approach integrating relevant neuroimaging, mapping, ontology, connectivity data and different possibilities to administer brain region dependent sets of parameters for large scale simulations offers the opportunity to analyze dynamics of single regions and region ensembles of a realistic rat brain neuronal network.
This article is published under license to BioMed Central Ltd.