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RETRACTED ARTICLE: Effects of Nano-particles on Histo-pathological changes of the fish

  • Ali Louei Monfared
  • Ali Mohammad Bahrami
  • Ehsan Hosseini
  • Salman Soltani
  • Minoo ShaddelEmail author
Research article

Abstract

Regarding fast development of the nanotechnology and the probably of it’s side effects on aquatic body organs, this study investigate the effects of nanosilver administration on histology of gill, kidney and biochemical parameters in common carp. The silver nanoparticles were synthesized in a one-step reduction process in an aqueous solution. 60 O. mykiss were obtained from a local commercial hatchery. Fish were divided randomly into four groups. Control group was kept in dechlorinated tap water without any add-on material. Experimental groups were exposed to concentration of 3, 300 and 1000 mg/L of nanosilver solution for eight weeks, respectively. Biochemical analyses of sera, histological alterations of the gill and kidney tissue were done. Aneurism in the secondary lamellae and hyperplasia of epithelium in gills, adhesion of the gill lamellae, inducing hyaline cast formation, significant decreasing in the glomerular diameter and formation of intra cytoplasmic vacuoles in the various urinary tubules were seen in experimental groups. The serum levels of total protein was decreased significantly (P < 0.05) by increasing nanosilver concentration but ALP, LDH, AST and ALT increased significantly (P < 0.05). It is concluded that nanosilver induces gill and kidney damages and changes the biochemical parameters of O. mykiss juveniles in different concentrations.

Keywords

Biochemistry Carp Gill Histology Kidney Nanosilver 

Notes

Acknowledgments

This study was financially supported by Ilam University Research Grant No: 206/5/D.

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Copyright information

© Monfared et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors and Affiliations

  • Ali Louei Monfared
    • 1
  • Ali Mohammad Bahrami
    • 1
  • Ehsan Hosseini
    • 1
  • Salman Soltani
    • 2
  • Minoo Shaddel
    • 3
    Email author
  1. 1.Faculty of Para-Veterinary MedicineUniversity of IlamIlamIran
  2. 2.Master of Sciences of Histology, Faculty of Veterinary MedicineUniversity of Shahid Chamran AhwazAhwazIran
  3. 3.Department of ParasitologyFaculty of Medicine, Aja University of Medical SciencesTehranIran

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