RETRACTED ARTICLE: Effects of Nano-particles on Histo-pathological changes of the fish
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Regarding fast development of the nanotechnology and the probably of it’s side effects on aquatic body organs, this study investigate the effects of nanosilver administration on histology of gill, kidney and biochemical parameters in common carp. The silver nanoparticles were synthesized in a one-step reduction process in an aqueous solution. 60 O. mykiss were obtained from a local commercial hatchery. Fish were divided randomly into four groups. Control group was kept in dechlorinated tap water without any add-on material. Experimental groups were exposed to concentration of 3, 300 and 1000 mg/L of nanosilver solution for eight weeks, respectively. Biochemical analyses of sera, histological alterations of the gill and kidney tissue were done. Aneurism in the secondary lamellae and hyperplasia of epithelium in gills, adhesion of the gill lamellae, inducing hyaline cast formation, significant decreasing in the glomerular diameter and formation of intra cytoplasmic vacuoles in the various urinary tubules were seen in experimental groups. The serum levels of total protein was decreased significantly (P < 0.05) by increasing nanosilver concentration but ALP, LDH, AST and ALT increased significantly (P < 0.05). It is concluded that nanosilver induces gill and kidney damages and changes the biochemical parameters of O. mykiss juveniles in different concentrations.
KeywordsBiochemistry Carp Gill Histology Kidney Nanosilver
This study was financially supported by Ilam University Research Grant No: 206/5/D.
- 3.Smith IC, Carson BL. Trace Metals in the Environment. Ann Arbor: An Arbor Science Publishers; 1977. p. 469.Google Scholar
- 7.Birge WJ, Zuiderveen JA. Transport, fate and effects of silver in environment [Abstracts]. 3rd International conference 1995, 6-9.Google Scholar
- 10.Van der Oost R, Beyer J, Vermeulen NPE. Fish bioaccumulation and biomarkers in environmental risk assessment: a review Environmental Toxicology and Pharmacology. J Fish Biolo. 2003;26:755–64.Google Scholar
- 13.Abdel-Hameid N-A. Physiological and Histopathological Alterations Induced by Phenol Exposure in Oreochromis aureus Juveniles. Tur J Fish Aqua Sci. 2007;7:131–8.Google Scholar
- 14.Patel JM, Bahadur A. Studies on the histopathological manifestations of sublethal toxicity of copper ions in Catla catla. (Hamilton). American-Eurasian J Toxicol Sci. 2011;4(1):01–5.Google Scholar
- 16.Kumar Das B, Mukherjee SS. A histopathological study of carp (Labeo rohita) exposed to hexa chlorocyclohexane. Vet Arch. 2000;70(4):169–80.Google Scholar
- 22.Wood C, Munger S, Galvez F, Hogstrand C. The physiology of silver toxicity in freshwater fish. In: Andren A, Bober T, editors. Transport, fate, and effects of silver in the environment [abstract]. Procee 2nd international conference. Madison: University of Wisconsin Sea Grant Institute; 1994. p. 109–14.Google Scholar
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