Genome Biology

, 20:247 | Cite as

Correction to: scBFA: modeling detection patterns to mitigate technical noise in large-scale single-cell genomics data

  • Ruoxin Li
  • Gerald QuonEmail author
Open Access

Correction to: Genome Biol

Following publication of the original article [1], the following two errors were found in formulae:

1) In the method section titled “Benchmarking dimensionality reduction methods for scRNA-seq”, the brackets should be removed from inside the square roots. The correct equation is shown below:
$$ \mathrm{MCC}=\frac{TP\ast TN- FP\ast FN}{\left(\sqrt{TP+ FP}\right)\ast \left(\sqrt{TP+ FN}\right)\ast \left(\sqrt{TN+ FP}\right)\ast \left(\sqrt{TN+ FN}\right)} $$
2) In the method section titled “Batch effect correction”, the position of superscript in the subscript are incorrect. The correct equation is shown below.
$$ {\mathbf{M}}_{\mathbf{sub}\left({i}^{\hbox{'}},j\right)}\sim P\left({g}^{-1}\left({\mathbf{x}}_{\mathbf{sub}\left({\mathbf{i}}^{\hbox{'}}\right)}^{\mathbf{T}}{\boldsymbol{\upbeta}}_{\mathbf{j}}+{\mathbf{z}}_{\mathbf{sub}\left({\mathbf{i}}^{\hbox{'}}\right)}^{\mathbf{T}}{\mathbf{a}}_{\mathbf{j}}+{u}_{\mathrm{sub}\left({i}^{\hbox{'}}\right)}+{\upsilon}_j\right)\right) $$


  1. 1.
    Li, Quon. scBFA: modeling detection patterns to mitigate technical noise in large-scale single-cell genomics data. Genome Biol. 2019;20:193 Scholar

Copyright information

© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

Authors and Affiliations

  1. 1.Graduate Group in BiostatisticsUniversity of California, DavisDavisUSA
  2. 2.Genome CenterUniversity of California, DavisDavisUSA
  3. 3.Department of Molecular and Cellular BiologyUniversity of California, DavisDavisUSA

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