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Biological Theory

, Volume 5, Issue 4, pp 344–356 | Cite as

Autism’s Direct Cause? Failure of Infant-Mother Eye Contact in a Complex Adaptive System

Article

Abstract

This article attempts to show why an experimental hypothesis is plausible and merits testing; in brief, the hypothesis is that autism begins with a failure in early learning and that changing the environment of early learning would dramatically change its incidence. Strong statistical evidence supporting this hypothesis has been published by Waldman et al. (2008), but to date this evidence has largely been ignored, perhaps because it challenges prevalent beliefs about autism. This article also suggests that the current epidemic of autism is serious enough, and intellectually mysterious enough, to merit attention from a wider community of brain scientists: New ideas are needed. A confirmation of this article’s hypothesis would have interesting implications for brain science.

Keywords

autism spectrum disorder complex adaptive system complexity environmental trigger infant-mother eye contact intersubjectivity oxytocin self-organized smartphone television 

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References

  1. Abrahams BS, Geschwind DH (2008) Advances in autism genetics: On the threshold of a new neurobiology. Nature Reviews Genetics 9: 341–355.CrossRefGoogle Scholar
  2. Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P (2007) The Molecular Biology of the Cell, 5th ed. New York: Garland Science.Google Scholar
  3. Als H, Tronic E, Brazelton TB (1980) Stages of early behavioral organization: The study of a sighted infant and a blind infant in interaction with their mothers. In: High-Risk Infants and Children (Field TM, ed), 181–204. New York: Academic Press.Google Scholar
  4. American Academy of Pediatrics, Committee on Public Education (2001) Children, Adolescents, and Television. Pediatrics 107: 423–426.CrossRefGoogle Scholar
  5. Andari E, Duhamel J-R, Zalla T, Herbrecht E, Leboyer M, Sirigu A (2010) Promoting social behavior with oxytocin in high-functioning autism spectrum disorders. Proceedings of the National Academy of Sciences USA 107(9): 4389–4394.CrossRefGoogle Scholar
  6. Anderson DR, Pempek, TA (2005) Television and very young children. American Behavioral Scientist 48: 505–522.CrossRefGoogle Scholar
  7. Arthur WB (1999) Complexity and the economy. Science 284: 107–109.CrossRefGoogle Scholar
  8. Auyeung B, Taylor K, Hackett G, Baron-Cohen S (2010) Foetal testosterone and autistic traits in 18- to 24-month-old children. Molecular Autism 1: 11.CrossRefGoogle Scholar
  9. Baron-Cohen S (1994) How to build a baby that can read minds: Cognitive mechanisms in mindreading. Cahiers de Psychologie Cognitive 13: 513–552.Google Scholar
  10. Baron-Cohen S, Wheelwright S, Jolliffe, T (1997) Is there a “language of the eyes”? Evidence from normal adults and adults with autism or Asperger syndrome. Visual Cognition 4(3): 311–331.CrossRefGoogle Scholar
  11. Baron-Cohen S, Wheelwright S, Skinner R, Martin J, Clubley E (2001) The autism spectrum quotient (AQ): Evidence from Asperger syndrome/high functioning autism, males and females, scientists and mathematicians. Journal of Autism and Developmental Disorders 31: 5–17.CrossRefGoogle Scholar
  12. Beebe B (2005) Mother-infant research informs mother-infant treatment. Psychoanalytic Study of the Child 60: 7–46.Google Scholar
  13. Beebe B, Lachmann FM (1998) Co-constructing inner and relational processes: Self and mutual regulation in infant research and adult treatment. Psychoanalytic Psychology 15(4): 480–516.CrossRefGoogle Scholar
  14. Beebe B, Lachmann FM, Jaffe J (1997) Mother-infant interaction structures and presymbolic self- and object representations. Psychoanalytic Dialogues 7(2): 133–182.CrossRefGoogle Scholar
  15. Bergman A (1985) From psychological birth to motherhood: The treatment of an autistic child with follow-up into her adult life as a mother. In: Parental Influences in Health and Disease (Anthony EJ, Pollock GH, eds), 91–120. Boston: Little, Brown.Google Scholar
  16. Bonabeau E, Theraulaz G, Deneubourg SA, Camzine S (1997) Self-organization in social insects. Trends in Ecology and Evolution 12(5): 188–193.CrossRefGoogle Scholar
  17. Bower B (2009) Joint attention provides clues to autism and cooperation: Different paths to childhood autism. Science News 176(10): 15.Google Scholar
  18. Broad Institute of MIT and Harvard (2008) Human gene count tumbles again. ScienceDaily (15 January). http://www.sciencedaily.com/releases/2008/01/080113161406.htm
  19. Brown R, Hobson RP, Lee A, Stevenson, J (1997) Are there “autistic like” features in congenitally blind children? Journal of Child Psychology and Psychiatry 38(6): 693–703.CrossRefGoogle Scholar
  20. Byrd R (2002) Report to the legislature on the principle findings from “The epidemiology of autism in California: A comprehensive pilot study.” http://www.ourstolenfuture.org/NewScience/behavior/2002/2002-10byrd.htm
  21. California Department of Developmental Services (2007) Autism spectrum disorders. Changes in the California caseload, an update: June 1987–June 2007. http://www.dds.ca.gov/autism/docs/AutismReport_2007.pdf
  22. Carver CS, Scheier MF (2000) Perspectives on Personality, 4th ed. Boston: Allyn and Bacon.Google Scholar
  23. Chimpanzee Sequencing and Analysis Consortium (2005) Initial sequence of the chimpanzee genome and comparison with the human genome. Nature 437: 69–87.CrossRefGoogle Scholar
  24. Christakis DA (2009) The effects of infant media usage: What do we know and what should we learn? Acta Paediatrica 98(1): 8–16.CrossRefGoogle Scholar
  25. Christakis DA (2010) Internet addiction: A 21st century epidemic? BioMed Central Medicine 8: 61. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972229/?tool=pubmed Google Scholar
  26. Christakis DA, Zimmerman FJ, DiGiuseppe DL, McCarthy CA (2004) Early television exposure and subsequent attentional problems in children. Pediatrics 113: 708–713.CrossRefGoogle Scholar
  27. Dunbar RIM (1992) Neocortex size as a constraint on group size in primates. Journal of Human Evolution 20: 469–493.CrossRefGoogle Scholar
  28. Elman JL, Bates EA, Johnson MH, Karmiloff-Smith A, Parisi D, Plunkett K (1998) Rethinking Innateness: A Connectionist Perspective on Development. Cambridge, MA: MIT Press.Google Scholar
  29. Elsabbagh M, Johnson MH (2009) Getting answers from babies about autism. Trends in Cognitive Sciences 14: 81–87.CrossRefGoogle Scholar
  30. Elsabbagh M, Volein A, Csibra G, Holmboe K, Garwood H, Tucker L, Krljes S, Baron-Cohen S, Bolton P, Charman T, Baird G, Johnson MH (2009) Neural correlates of eye gaze processing in the infant broader autism phenotype. Biological Psychiatry 65: 31–38.CrossRefGoogle Scholar
  31. Emery NJ (2000) The eyes have it: The neuroethology, function and evolution of social gaze. Neuroscience and Biobehavioral Reviews 24: 581–604.CrossRefGoogle Scholar
  32. Farroni T, Csibra G, Simion F, Johnson MH (2002) Eye-contact detection in humans from birth. Proceedings of the National Academy of Sciences USA 99: 9602–9605.CrossRefGoogle Scholar
  33. Fraiberg S (1977) Insights from the Blind: Comparative Studies of Blind and Sighted Infants. New York: Basic Books.Google Scholar
  34. Freedman D (1964) Smiling in blind infants and the issue of innate vs. acquired. Journal of Child Psychology and Psychiatry 47: 171–184.CrossRefGoogle Scholar
  35. Fries ABW, Ziegler TE, Kurian JR, Jacoris S, Pollak SD (2005) Early experience in humans is associated with changes in neuropeptides critical for regulating social behavior. Proceedings of the National Academy of Sciences USA 102: 17237–17240.CrossRefGoogle Scholar
  36. Gans C, Parsons TS (1973) Biology of the Reptiles, 4, Morphology D, 104. London: Academic Press.Google Scholar
  37. Ganz ML (2006) The costs of autism. In: Understanding Autism: From Basic Neuroscience to Treatment (Moldin SO, Rubenstein JLR, eds), 475–502. New York: CRC Press.CrossRefGoogle Scholar
  38. Ganz ML (2007) The lifetime distribution of the incremental societal costs of autism. Archives of Pediatric, Adolescent Medicine 161(4): 343–349.CrossRefGoogle Scholar
  39. Gell-Mann M (1994) The Quark and the Jaguar: Adventures in the Simple and the Complex. New York: Henry Holt.Google Scholar
  40. Gergely G (2001) The obscure object of desire: “Nearly, but clearly not, like me.” Contingency preference in normal children versus children with autism. Bulletin of the Menninger Clinic 65: 411–426.CrossRefGoogle Scholar
  41. Gergely G, Watson JS (1996) The social biofeedback theory of parental affect mirroring. International Journal of Psycho-Analysis 77: 1181–1212.Google Scholar
  42. Gillberg C, Wing L (1999) Autism: Not an extremely rare disorder. Acta Psychiatrica Scandinavica 99(6): 399–406.CrossRefGoogle Scholar
  43. Guastella AJ, Einfeld SL, Gray KM, Rinehart NJ, Tonge BJ, Lambert TJ, Hickie IB (2010) Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders. Biological Psychiatry 67: 692–694.CrossRefGoogle Scholar
  44. Haaf RA, Bell RQ (1967) A facial dimension in visual discrimination by human infants. Child Development 38: 892–899.Google Scholar
  45. Haith MM (1966) The response of the human newborn to visual movement. Journal of Experimental Child Psychology 3: 235–243.CrossRefGoogle Scholar
  46. Hobson RP, Lee A, Brown R (1999) Autism and congenital blindness. Journal of Autism and Developmental Disorders 29(1): 45–56.CrossRefGoogle Scholar
  47. Holland J (1998) Emergence from Chaos to Order. Reading, MA: Perseus.Google Scholar
  48. Hertz-Picciotto I, Delwiche L (2009) The rise of autism and the role of age in diagnosis. Epidemiology 20: 84–90.CrossRefGoogle Scholar
  49. Jaffe J, Beebe B, Feldstein S, Crown CL, Jasnow MD (2001) Rhythms of dialogue in infancy: Coordinated timing in development. Monograph of the Society for Research in Child Development 66: i–viii, 1–132.Google Scholar
  50. James I (2003) Singular scientists. Journal of the Royal Society of Medicine 96(1): 36–39.CrossRefGoogle Scholar
  51. Janzen DH, Hallwachs W, Burns JM (2010) A tropical horde of counterfeit predator eyes. Proceedings of the National Academy of Sciences USA 107: 11659–11665.CrossRefGoogle Scholar
  52. Kaiser Family Foundation (2003) Zero to Six: Electronic Media in the Lives of Infants, Toddlers, and Preschoolers. Menlo Park, CA: Kaiser Family Foundation.Google Scholar
  53. Kaiser Family Foundation (2006) The Media Family: Electronic Media in the Lives of Infants, Toddlers, Preschoolers, and their Parents. Menlo Park, CA: Kaiser Family Foundation. http://www.kff.org/entmedia/upload/7500.pdf Google Scholar
  54. Kaiser MD, Hudac CM, Shultza S, Leea SM, Cheung C, Berken AM, Deen B, Pitskel NB, Sugrue DR, Voos AC, Saulnier CA, Ventola P, Wolf JM, Klin A, Vander Wyk BC, Pelphrey KA (2010) Neural signatures of autism. Proceedings of the National Academy of Sciences USA 107: 21223–21228.CrossRefGoogle Scholar
  55. Karmiloff-Smith A (2009) Nativism versus neuroconstructivism: Rethinking the study of developmental disorders. Developmental Psychology 45: 56–63.CrossRefGoogle Scholar
  56. Klin A, Jones W (2007) Embodied psychoanalysis? Or, on the confluence of psychodynamic theory and developmental science. In: Developmental Science and Psychoanalysis: Integration and Innovation (Mayes L, Fonagy P, Target M, eds), 5–38. London: Karnac.Google Scholar
  57. Klin A, Jones W, Schultz R, Volkmar F, Cohen D (2002) Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autism. Archives of General Psychiatry 59(9): 809–816.CrossRefGoogle Scholar
  58. Klin A, Lin DJ, Gorrindo P, Ramsay G, Jones W (2009, 14 May) Two-year olds with autism orient to non-social contingencies rather than biological motion. Nature Letters 459 (7244): 257–261.CrossRefGoogle Scholar
  59. Kogan MD, Blumberg SJ, Schieve LA, Boyle CA, Perrin JM, Ghandour RM, Singh GK, Strickland BB, Trevathan E, van Dyck PC (2009) National children’s health survey report: Prevalence of parent-reported diagnosis of autism spectrum disorder among children in the US, 2007. Pediatrics 124(5): 1395–1403.CrossRefGoogle Scholar
  60. Lachmann FM (2000) Transforming Aggression: Psychotherapy with the Difficult-to-Treat Patient, 74–86. Northvale, NJ: Jason Aronson.Google Scholar
  61. Levin SA (1998) Ecosystems and the biosphere as complex adaptive systems. Ecosystems 1: 431–436.CrossRefGoogle Scholar
  62. Loeuille N (2009) Evolution of communities and ecosystems. In: The Princeton Guide to Ecology (Levin SA, ed), 414–421. Princeton, NJ: Princeton University Press.Google Scholar
  63. Lovgren S (2005) Chimps, humans 96 percent the same, gene study finds. National Geographic News (31 August).Google Scholar
  64. Maestro S, Muratori F, Barbieri F, Casella C, Cattaneo V, Cavallaro MC, Cesari A, Milone A, Rizzo L, Viglione V, Stern DD, Palacio-Espasa F (2001) Early behavioral development in autistic children: The first 2 years of life through home movies. Psychopathology 34: 147–152.CrossRefGoogle Scholar
  65. McDowell MJ (2002) The image of the mother’s eye: Autism and early narcissistic injury. http://cogprints.org/2593/
  66. McDowell MJ (2004a) Autism, early narcissistic injury and self-organization: A role for the image of the mother’s eyes? Journal of Analytical Psychology 49(4): 495–520.CrossRefGoogle Scholar
  67. McDowell MJ (2004b) Is autism statistically linked to early non-maternal child care? Dynamical Psychology. http://www.goertzel.org/dynapsyc/2004/Autism04.htm
  68. McKinney ML, McNamara KJ (1991) Heterochrony: The Evolution of Ontogeny. New York: Plenum Press.CrossRefGoogle Scholar
  69. Michael CR (1969) Retinal processing of visual images. Scientific American May: 104–115.Google Scholar
  70. Mitchell M (2009) Complexity: A Guided Tour. New York: Oxford University Press.Google Scholar
  71. Muratori M, Maestro S (2007) Autism as a downstream effect of primary difficulties in inter-subjectivity interacting with abnormal development of brain connectivity. International Journal for Dialogical Science 2: 93–118.Google Scholar
  72. Olmsted D (2005a) The age of autism: The Amish anomaly. Washington Times (18 April).Google Scholar
  73. Olmsted D (2005b) The age of autism: Julia. Washington Times (19 April).Google Scholar
  74. Poitras C (2010) Recovery from Autism. UConn Today (13 September). http://today.uconn.edu/?p=20440
  75. Rimmele U, Hediger K, Heinrichs M, Klaver P (2009) Oxytocin makes a face in memory familiar. Journal of Neuroscience 29: 38–42.CrossRefGoogle Scholar
  76. Rutter ML, Kreppner JM, O’Connor TG (2001) Specificity and heterogeneity in children’s responses to profound institutional privation. British Journal of Psychiatry 179: 97–103.CrossRefGoogle Scholar
  77. Salapatek P (1975) Pattern perception in early infancy. In: Infant Perception: From Sensation to Cognition, Volume I: Basic Visual Processes (Cohen LB, Salapatek P, eds), 144–248. New York: Academic Press.Google Scholar
  78. Scheffer M (2009) Alternative stable states and regime shifts in ecosystems. In: The Princeton Guide to Ecology (Levin SA, ed), 395–404. Princeton, NJ: Princeton University Press.Google Scholar
  79. Scherer SW, Szatmari P, Vicente AM, Vieland VJ, Wijsman EM, Sutcliffe JS, et al. (2010) Functional impact of global rare copy number variation in autism spectrum disorders. Nature 466: 368–372.CrossRefGoogle Scholar
  80. Sharma J, Alessandra A, Sur M (2000) Induction of visual orientation modules in auditory cortex. Nature 404: 841–847.CrossRefGoogle Scholar
  81. Spitz RA, Wolf KM (1946) The smiling response: A contribution to the ontogenesis of social relations. Genetic Psychology Monographs 34: 57–125.Google Scholar
  82. Stern DN (1977) The First Relationship. Cambridge, MA: Harvard University Press.Google Scholar
  83. Stern DN (1985) The Interpersonal World of the Infant. New York: Basic Books.Google Scholar
  84. Stern DN, Sander LW, Nahum JP, Harrison AM, Lyons-Ruth K, Morgan AC, Bruschwiler-Stern N, Tronic EZ (1998) Non-interpretive methods in psychoanalytic therapy: The “something more” than interpretation. International Journal of Psycho-Analysis 79: 903–931.Google Scholar
  85. Stolorow RD (1997) Dynamic, dyadic, intersubjective systems: An evolving paradigm for psychoanalysis. Psychoanalytic Psychology 14(3): 337–346.CrossRefGoogle Scholar
  86. Strömland K, Sjögreen L, Miller M, Gillberg C, Wentz E, Johansson M, Nylen O, Danielsson A, Jacobsson C, Andersson J, Fernell E (2002) Mobius sequence: A Swedish multidiscipline study. European Journal of Paediatric Neurology 6: 35–45.CrossRefGoogle Scholar
  87. Trepagnier C (1998) Autism etiology: A face-processing perspective. Brain and Cognition 37: 158–160.Google Scholar
  88. Waldman M, Nicholson S, Adilov N (2006) Does television cause autism? Working paper at http://www.nber.org/papers/w12632
  89. Waldman M, Nicholson S, Adilov N, Williams J (2008) Autism prevalence and precipitation rates in California, Oregon, and Washington counties. Archive of Pediatric Adolescent Medicine 162: 1026–1034.CrossRefGoogle Scholar
  90. Winnicott DW ([1971] 1986) Playing and Reality. New York: Routledge.Google Scholar
  91. Wood WB, Crowther RA (1983) Long tail fibers: Genes, proteins, assembly, and structure. In: Bacteriophage T4 (Mathews CK, Kutter EM, Mosig G, Berget PB, eds), 263. Washington, DC: American Society for Microbiology.Google Scholar
  92. Yazbak, FE (2003) Autism in the United States: A perspective. Journal of American Physicians and Surgeons 8(4): 103–107.Google Scholar

Copyright information

© Konrad Lorenz Institute for Evolution and Cognition Research 2011

Authors and Affiliations

  1. 1.New YorkUSA

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