The European Physical Journal Special Topics

, Volume 213, Issue 1, pp 355–365 | Cite as

Diffraction studies on natural and model lipid bilayers

  • F. Sebastiani
  • R. Harvey
  • S. Khanniche
  • J.-B. Artero
  • M. Haertlein
  • G. Fragneto
Regular Article

Abstract

In this study we have used neutron diffraction to examine the swelling behaviour and bilayer parameters of membranes reconstituted from polar lipids extracted from B. subtilis and model systems composed of synthetic phospholipids. Evidence for phase separation in the model system (lacking in Lysyl-PG, L-PG) is discussed in relation to its possible contribution to membrane domain formation through lipid-lipid interactions. Comparing these results with those obtained from the bilayers composed of lipids extracted from bacterial cells gives us some indication of the role of L-PG in the B. subtilis plasma membrane.

Keywords

European Physical Journal Special Topic Lamellar Spacing Natural Lipid Repeat Spacing Synthetic Lipid 

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Copyright information

© EDP Sciences and Springer 2012

Authors and Affiliations

  • F. Sebastiani
    • 1
    • 2
  • R. Harvey
    • 3
  • S. Khanniche
    • 1
  • J.-B. Artero
    • 1
    • 4
  • M. Haertlein
    • 1
  • G. Fragneto
    • 1
  1. 1.Institut Laue LangevinGrenobleFrance
  2. 2.Dipartimento di Fisica, Università di Roma “Tor Vergata”RomaItaly
  3. 3.Institute of Pharmaceutical Science, King’s College LondonLondonUK
  4. 4.Macromolecular Structure Research Group, Keele UniversityStaffordshireUK

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