Automatic segmentation of the left ventricle in a cardiac MR short axis image using blind morphological operation

  • Mehreen Irshad
  • Nazeer Muhammad
  • Muhammad Sharif
  • Mussarat Yasmeen
Regular Article


Conventionally, cardiac MR image analysis is done manually. Automatic examination for analyzing images can replace the monotonous tasks of massive amounts of data to analyze the global and regional functions of the cardiac left ventricle (LV). This task is performed using MR images to calculate the analytic cardiac parameter like end-systolic volume, end-diastolic volume, ejection fraction, and myocardial mass, respectively. These analytic parameters depend upon genuine delineation of epicardial, endocardial, papillary muscle, and trabeculations contours. In this paper, we propose an automatic segmentation method using the sum of absolute differences technique to localize the left ventricle. Blind morphological operations are proposed to segment and detect the LV contours of the epicardium and endocardium, automatically. We test the benchmark Sunny Brook dataset for evaluation of the proposed work. Contours of epicardium and endocardium are compared quantitatively to determine contour’s accuracy and observe high matching values. Similarity or overlapping of an automatic examination to the given ground truth analysis by an expert are observed with high accuracy as with an index value of 91.30% . The proposed method for automatic segmentation gives better performance relative to existing techniques in terms of accuracy.


  1. 1.
    M. Nichols, N. Townsend, P. Scarborough, M. Rayner, Eur. Heart J. 34, 3007 (2013)CrossRefGoogle Scholar
  2. 2.
    Ahmed Naseer, Linardi Daniele, Muhammad Nazeer, Chiamulera Cristiano, Fumagalli Guido, San Biagio Livio, A. Gebrie Mebratu, Aslam Muhammad, Battista Luciani Giovanni, Faggian Giuseppe, Front. Pharmacol. 8, 645 (2017)CrossRefGoogle Scholar
  3. 3.
    S. Mendis, P. Puska, B. Norrving, Global Atlas on Cardiovascular Disease Prevention and Control (World Health Organization, 2011)Google Scholar
  4. 4.
    M. Nichols, N. Townsend, P. Scarborough, M. Rayner, Eur. Heart J. 35, 2950 (2014)CrossRefGoogle Scholar
  5. 5.
    Aslam Adnan, Bashir Yasir, Rafiq Muhammad, Haider Faiza, Muhammad Nazeer, Bibi Nargis, Electron. J. Biol. 13, 1 (2017)Google Scholar
  6. 6.
    Bashir Yasir, Aslam Adnan, Kamran Muhammad, Imran Qureshi Muhammad, Jahangir Adnan, Rafiq Muhammad, Bibi Nargis, Muhammad Nazeer, Molecules 22, 867 (2017)CrossRefGoogle Scholar
  7. 7.
    P.P. Sengupta, J. Korinek, M. Belohlavek et al., J. Am. Coll. Cardiol. 48, 1988 (2006)CrossRefGoogle Scholar
  8. 8.
    Z. Ma, J.M. Tavares, R.N. Jorge, T. Mascarenhas, Comput. Methods Biomech. Biomed. Eng. 13, 235 (2010)CrossRefGoogle Scholar
  9. 9.
    A. Ferreira, F. Gentil, J.M. Tavares, Comput. Methods Biomech. Biomed. Eng. 17, 888 (2014)CrossRefGoogle Scholar
  10. 10.
    Z. Ma, J.M. Tavares, J. Med. Syst. 39, 177 (2015)CrossRefGoogle Scholar
  11. 11.
    M.A. Guttman, E. Zerhouni, E.R. McVeigh, Comput. Graph. Appl., IEEE 17, 30 (1997)CrossRefGoogle Scholar
  12. 12.
    P. Morais, J.L. Vilaça, J. Ector, J. D’hooge, J.M. Tavares, J. Med. Dev. 11, 010801 (2017)CrossRefGoogle Scholar
  13. 13.
    N.G. Keenan, D.J. Pennell, Echocardiography 24, 185 (2007)CrossRefGoogle Scholar
  14. 14.
    V.K. Rathi, R.W. Biederman, Curr. Cardiol. Rep. 6, 55 (2004)CrossRefGoogle Scholar
  15. 15.
    Z. Ma, J.M. Tavares, R.N. Jorge, A Review on the Current Segmentation Algorithms for Medical Images, in Proceedings of the 1st International Conference on Imaging Theory and Applications (IMAGAPP) 2009,
  16. 16.
    D.S. Jodas, A.S. Pereira, J.M. Tavares, Exp. Syst. Appl. 46, 1 (2016)CrossRefGoogle Scholar
  17. 17.
    R.B. Oliveira, E. Mercedes Filho, Z. Ma, J.P. Papa, A.S. Pereira, J.M. Tavares, Computer methods and programs in biomedicine 131, 127 (2016)CrossRefGoogle Scholar
  18. 18.
    I.R. Valente, P.C. Cortez, E.C. Neto, J.M. Soares, V.H. de Albuquerque, J.M. Tavares, Computer methods and programs in Biomedicine 124, 91 (2016)CrossRefGoogle Scholar
  19. 19.
    J.S. Suri, Pattern Anal. Appl. 3, 209 (2000)CrossRefGoogle Scholar
  20. 20.
    R.M. Smith, A. Matiukas, C.W. Zemlin, A.M. Pertsov, Microsc. Res. Tech. 71, 510 (2008)CrossRefGoogle Scholar
  21. 21.
    Y. Huang, X. Sun, G. Hu, Y. Huang, Microsc. Res. Tech. 75, 388 (2012)CrossRefGoogle Scholar
  22. 22.
    C. Petitjean, J.N. Dacher, Med. Image Anal. 15, 169 (2011)CrossRefGoogle Scholar
  23. 23.
    Irshad Mehreen, Muhammad Sharif, Mussarat Yasmin, Amjad Khan, Curr. Med. Imaging Rev. 13, 1 (2017)Google Scholar
  24. 24.
    Amin Katouzian, Prakash Ashwin, Konofagou Elisa (Editors), A new automated technique for left-and right-ventricular segmentation in magnetic resonance imaging, in 28th Annual International Conference of the IEEE. Engineering in Medicine and Biology SocietyGoogle Scholar
  25. 25.
    J. Cousty, L. Najman, M. Couprie, S. Clément-Guinaudeau, T. Goissen, J. Garot, Image Vision Comput. 28, 1229 (2010)CrossRefGoogle Scholar
  26. 26.
    Bibi Nargis, Kleerekoper Anthony, Muhammad Nazeer, Cheetham Barry, SpringerPlus 5, 931 (2016)CrossRefGoogle Scholar
  27. 27.
    Bibi Nargis, Muhammad Nazeer, Cheetham Barry, Circ. Syst. Signal Process. 37, 901 (2018)CrossRefGoogle Scholar
  28. 28.
    A. Eslami, A. Karamalis, A. Katouzian, N. Navab, Med. Image Anal. 17, 236 (2013)CrossRefGoogle Scholar
  29. 29.
    Singh Samreen Arifa Baljeet, Jahangir Adnan, Muhammad Nazeer, U.P.B. Sci. Bull., Ser. D 79, 13 (2017)Google Scholar
  30. 30.
    Usman Muhammad, Saba Kiran, Han Dong-Pyo, Muhammad Nazeer, Superlattices Microstruct. 113, 585 (2018)ADSCrossRefGoogle Scholar
  31. 31.
    Usman Muhammad, Saba Kiran, Han Dong-Pyo, Muhammad Nazeer, Farwa Shabieh, Muhammad Rafique, Saba Tanzila, AIP Adv. 8, 015005 (2018)ADSCrossRefGoogle Scholar
  32. 32.
    S.M. Abo-Dahab, Jahangir Adnan, Muhammad Nazeer, Farwa Shabieh, Bashir Yasir, Usman Muhammad, Results Phys. 8, 793 (2018)ADSCrossRefGoogle Scholar
  33. 33.
    Y. Atwa Sarhan, M. Nazeer, J. Adnan, Rehman Nadia, Eur. Phys. J. Plus 132, 301 (2017)CrossRefGoogle Scholar
  34. 34.
    M. Marino, F. Veronesi, G. Tarroni, V. Mor-Avi, A.R. Patel, C. Corsi (Editors), Fully automated assessment of left ventricular volumes, function and mass from cardiac MRI, in Computing in Cardiology Conference (CinC) (IEEE, 2014) pp. 109--112Google Scholar
  35. 35.
    C.M. Nambakhsh, J. Yuan, K. Punithakumar et al., Med. Image Anal. 17, 1010 (2013)CrossRefGoogle Scholar
  36. 36.
    Farwa Shabieh, Muhammad Nazeer, Shah Tariq, Ahmad Sohail, 3D Res. 8, 26 (2017)CrossRefGoogle Scholar
  37. 37.
    Muhammad Nazeer, Bibi Nargis, IET Image Process. 9, 795 (2015)CrossRefGoogle Scholar
  38. 38.
    Farwa Shabieh, Shah Tariq, Muhammad Nazeer, Bibi Nargis, Jahangir Adnan, Arshad Sidra, Int. J. Adv. Comput. Sci. Appl. 8, 360 (2017)Google Scholar
  39. 39.
    Muhammad Nazeer, Bibi Nargis, Jahangir Adnan, Mahmood Zahid, Pattern Anal. Appl. (2017)
  40. 40.
    D. Grosgeorge, C. Petitjean, J.N. Dacher, S. Ruan, Comput. Vision Image Underst. 117, 1027 (2013)CrossRefGoogle Scholar
  41. 41.
    I.B. Ayed, K. Punithakumar, S. Li, A. Islam, J. Chong (Editors), Left ventricle segmentation via graph cut distribution matching, in Medical Image Computing and Computer-Assisted Intervention--MICCAI 2009Google Scholar
  42. 42.
    Muhammad Nazeer, Bibi Nargis, Qasim Iqbal, Jahangir Adnan, Mahmood Zahid, Pattern Anal. Appl. (2017)
  43. 43.
    Muhammad Nazeer, Bibi Nargis, Wahab Abdul, Mahmood Zahid, Akram Tallha, Rameez Naqvi Syed, Sook Oh Hyun, Kim Dai-Gyoung, Comput. Electr. Eng. (2017)
  44. 44.
    M.R. Kaus, J. von Berg, J. Weese, W. Niessen, V. Pekar, Med. Image Anal. 8, 245 (2004)CrossRefGoogle Scholar
  45. 45.
    Attique Khan Muhammad, Akram Tallha, Sharif Muhammad, Younus Javed Muhammad, Muhammad Nazeer, Yasmin Mussarat, Pattern Anal. Appl. (2018)
  46. 46.
    Muhammad Nazeer, Kim Dai-Gyoung, Resolution Enhancement for Digital Off-Axis Hologram Reconstruction, in Iaeng Transactions on Engineering Technologies (Springer, Dordrecht, 2013) pp. 431--43Google Scholar
  47. 47.
    Mahmood Zahid, Ali Tauseef, Muhammad Nazeer, Bibi Nargis, Shahzad Imran, Azmat Shoaib, KSII Trans. Internet Inf. Syst. 11, 6069 (2017)Google Scholar
  48. 48.
    Mahmood Zahid, Muhammad Nazeer, Bibi Nargis, Ali Tauseef, Fractals 25, 1750025 (2017)ADSCrossRefGoogle Scholar
  49. 49.
    Y. Wu, Y. Wang, Y. Jia, Comput. Vision Image Underst. 117, 990 (2013)CrossRefGoogle Scholar
  50. 50.
    Y. Lu, P. Radau, K. Connelly, A. Dick, G.A. Wright (Editors), Segmentation of left ventricle in cardiac cine MRI: An automatic image-driven method, in Functional Imaging and Modeling of the Heart (Springer, Berlin, Heidelberg, 2009) pp. 339--347Google Scholar
  51. 51.
    Q. Duan, E.D. Angelini, A.F. Laine, Comput. Methods Progr. Biomed. 98, 223 (2010)CrossRefGoogle Scholar
  52. 52.
    Muhammad Nazeer, Sharif Muhammad, Amin Jaweria, Mehboob Riffat, Bibi Nargis, Ahmed Naseer, Front. Pediatr. 6, 6 (2018)CrossRefGoogle Scholar
  53. 53.
    Mughal Bushra, Muhammad Nazeer, Sharif Muhammad, Saba Tanzila, Rehman Amjad, Biomed. Res. 28, 5041 (2017)Google Scholar
  54. 54.
    Mughal Bushra, Sharif Muhammad, Muhammad Nazeer, Eur. Phys. J. Plus 132, 266 (2017)CrossRefGoogle Scholar
  55. 55.
    Mughal Bushra, Sharif Muhammad, Muhammad Nazeer, Saba Tanzila, Microsc. Res. Tech. 81, 171 (2017)CrossRefGoogle Scholar
  56. 56.
    M.M. Hadhoud, M.I. Eladawy, A. Farag, F.M. Montevecchi, U. Morbiducci, Am. J. Biomed. Eng. 2, 131 (2012)CrossRefGoogle Scholar
  57. 57.
    P. Morais, J.L. Vilaça, S. Queirós, F. Bourier, I. Deisenhofer, J.M. Tavares, J. D’hooge, Med. Image Anal. 42, 102 (2017)CrossRefGoogle Scholar
  58. 58.
    H. Hu, H. Liu, Z. Gao, L. Huang, Magn. Reson. Imaging 31, 575 (2013)CrossRefGoogle Scholar
  59. 59.
    P. Radau, Y. Lu, K. Connelly, G. Paul, A. Dick, G. Wright, Evaluation framework for algorithms segmenting short axis cardiac MRI in The MIDAS Journal-Cardiac MR Left Ventricle Segmentation Challenge (2009)
  60. 60.
    N. Muhammad, N. Bibi, Z. Mahmood, D.G. Kim, SpringerPlus. 4, 832 (2015)CrossRefGoogle Scholar
  61. 61.
    N. Muhammad, N. Bibi, Z. Mahmood, T. Akram, S.R. Naqvi, PloS ONE 12, e0176979 (2017)CrossRefGoogle Scholar
  62. 62.
    Daniel A. Auger, Zhong Xiaodong, H. Epstein Frederick, M. Meintjes Ernesta, S. Spottiswoode Bruce, J. Cardiovasc. Magn. Reson. 16, 8 (2014)CrossRefGoogle Scholar
  63. 63.
    Debiao Li, Haacke E. Mark, Dávila-Román Victor G., J. Magn. Reson. Imaging 6, 690 (1996)CrossRefGoogle Scholar
  64. 64.
    Y.L. Lu, K.A. Connelly, A.J. Dick, G.A. Wright, P.E. Radau, Quant. Imaging Med. Surg. 3, 200 (2013)Google Scholar
  65. 65.
    H. Hu, Z. Gao, L. Liu et al., PloS ONE 9, e114760 (2014)ADSCrossRefGoogle Scholar

Copyright information

© Società Italiana di Fisica and Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Computer SciencesCOMSATS Institute of Information TechnologyWah CanttPakistan
  2. 2.Department of MathematicsCOMSATS Institute of Information TechnologyWah CanttPakistan

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