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X-ray radiation of poly-L-arginine hydrochloride and multilayered DNA-coatings

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Abstract

The aim of this work was to determine the chemical changes induced in thin films of the dry polypeptide poly-L-arginine hydrochloride and its mixture with calf thymus deoxyribonucleic acid (DNA) during 5 h of soft X-ray exposure. The physical and chemical effects of the soft X-ray irradiation were studied using X-ray Photoelectron Spectroscopy (XPS). Analysis of O1s, N1s and C1s features in XPS spectra reveals the existence of several routes of radiation-induced decomposition and shows quantitative and qualitative changes.

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Authors and Affiliations

  1. The Open University, Department of Physical Sciences, Walton Hall, Milton Keynes, MK7 6AA, UK

    Agnieszka Stypczyńska & Nigel Mason

  2. The Open University, Engineering and Innovation, Walton Hall, Milton Keynes, MK7 6AA, UK

    Tony Nixon

Authors
  1. Agnieszka Stypczyńska
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  2. Tony Nixon
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  3. Nigel Mason
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Correspondence to Agnieszka Stypczyńska.

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Stypczyńska, A., Nixon, T. & Mason, N. X-ray radiation of poly-L-arginine hydrochloride and multilayered DNA-coatings. Eur. Phys. J. D 68, 333 (2014). https://doi.org/10.1140/epjd/e2014-40845-8

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  • DOI: https://doi.org/10.1140/epjd/e2014-40845-8

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