Impact of network activity on noise delayed spiking for a Hodgkin-Huxley model
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In a Hodgkin-Huxley neuron model driven just above threshold, external noise can increase both jitter and latency of the first spike, an effect called “noise delayed decay” (NDD). This phenomenon is important when considering how neuronal information is represented, thus by the precise timing of spikes or by their rate. We examine how NDD can be affected by network activity by varying the model's membrane time constant, τm. We show that NDD is significant for small τm or high network activity, and decreases for large τm, or low network activity. Our results suggest that for inputs just above threshold, the activity of the network constrains the neuronal coding strategy due to, at least in part, the NDD effect.
PACS.05.40.-a Fluctuation phenomena, random processes, noise, and Brownian motion 87.10.+e General theory and mathematical aspects 87.16.-b Subcellular structure and processes
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- E.D. Adrian, J. Physiol. (Lond.) 61, 49 (1926) Google Scholar
- M. Abeles, Corticonics: Neural Circuitry of the Cerebral Cortex (Cambridge, Cambridge University Press, 1991) Google Scholar
- M. Abeles, H. Bergman, E. Magalit, A. Vaadia, J. Neurophysiol. 70, 1629 (1993) Google Scholar
- F. Rieke, D. Warland, R. de Ruyter van Steveninck, W. Bialek, Spikes - Exploring the Neural Code (Cambridge, MIT Press, 1996) Google Scholar
- W. Bair, C. Koch, Neural Comput. 8, 1185 (1996) Google Scholar
- P. Reinagel, R.C. Reid, J. Neurocsi. 20, 5392 (2000) Google Scholar
- N.V. Agudov, A.N. Malakhov, Int. J. Bifurcati. Chaos 5, 531 (1995); A.N. Malakhov, A.L. Pankratov, Physica C 269, 46 (1996); R.N. Mantegna, B. Spagnolo, Phys. Rev. Lett. 76, 563 (1996); N.V. Agudov, Phys. Rev. E 57, 2618 (1998), N.V. Agudov, A.N. Malakhov, Phys. Rev. E 60, 6333 (1999) CrossRefGoogle Scholar
- A.L. Hodgkin, A.F. Huxley, J. Physiol. (Lond.) 117, 500 (1952) Google Scholar
- B.W. Connors, M.J. Gutnick, J. Prince, J. Neurophysiol. 48, 1302 (1982) Google Scholar